Table 2 Associations of galectin-3 and fibulin-1 levels with clinical and glucometabolic parameters

From: Galectin-3 and fibulin-1 in systolic heart failure - relation to glucose metabolism and left ventricular contractile reserve

	Galectin-3		Fibulin-1
Parameter	β (SE)	P-Value	β (SE)	P-Value
Age, per year	0.16 (0.23)	0.05	0.36 (0.12)	<0.001
Sex	0.04 (0.07)	0.59	−0.09 (2.75)	0.29
Ischemic heart disease	−0.01 (0.07)	0.90	−0.009 (2.71)	0.92
NYHA I + II vs. III + IV	0.16 (0.09)	0.06	0.08 (3.37)	0.34
Atrial fibrillation	0.17 (0.07)	0.03	0.17 (2.83)	0.03
Diabetes mellitus	0.27 (0.07)	0.001	0.16 (2.62)	0.05
eGFR, per ml/min/1.73 m²	−0.49 (0.10)	<0.001	−0.33 (0.06)	<0.001
Metabolism
BMI, per kg/m²	−0.04 (0.006)	0.63	−0.12 (0.25)	0.14
FPG, per mmol/L	0.19 (0.02)	0.02	−0.07 (1.37)	0.44
2hPG, per mmol/L	0.15 (0.01)	0.09	0.26 (0.42)	0.004
HbA1C, per mmol/mol	0.25 (0.16)	0.02	0.21 (0.14)	0.009
HOMA-IR, per unit	0.17 (0.01)	0.06	−0.08 (0.52)	0.36
Biomarkers
NT-proBNP per pg/mL	0.30 (0.12)	<0.001	0.38 (2.24)	<0.001

Univariable regression models
2hPG 2 h plasma glucose, BMI Body mass index, FPG Fasting plasma glucose, GFR Glomerular filtration rate, HOMA-IR Homeostatic model assessment of insulin resistance, NT-proBNP N-terminal pro B-natriuretic peptide, NYHA NYHA functional class

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