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Table 4 Cox proportional hazard model of baseline biochemical risk factors for the development of major adverse cardiovascular events stratified by acute coronary syndrome and elective PCI subjects

From: The burden of major adverse cardiac events in patients with coronary artery disease

  Acute coronary syndrome Elective PCI
Baseline data Univariate analysis
HR (95% CI)
P value Multivariate model HR (95% CI) P-value Univariate analysis
HR (95% CI)
P value Multivariate model HR (95% CI) P value
Body mass index 0.98 (0.95–1.01) 0.135    0.99 (0.97–1.03) 0.942   
Waist circumference 1.01 (0.99–1.02) 0.131    1.01 (0.99–1.02) 0.172   
Waist to hip ratio 3.45 (1.30–7.40) 0.016    3.56 (1.29–7.03) 0.019   
Systolic BP 0.99 (0.99–1.00) 0.701    1.01 (0.99–1.01) 0.146   
Diastolic BP 0.24 (0.07–0.90) 0.034    0.15 (0.02–0.97) 0.046   
HbA1C 1.06 (0.99–1.11) 0.063    1.06 (0.99–1.16) 0.192   
Fasting glucose 3.98 (2.24–6.98) <0.0001    3.82 (1.85–7.66) 0.0004   
Total cholesterol 0.43 (0.24–0.91) 0.030    1.04 (0.30–3.61) 0.946   
Triglyceride 0.99 (0.99–1.00) 0.121    0.99 (0.99–1.00) 0.154   
HDL-cholesterol 0.29 (0.11–0.77) 0.014    0.30 (0.11–0.83) 0.021   
LDL-cholesterol 1.00 (0.99–1.00) 0.447    1.00 (0.99–1.01) 0.221   
Uric acid 1.00 (0.96–1.03) 0.981    1.17 (1.09–1.26) <0.0001 1.14 (1.01–1.28) 0.041
Creatinine 1.10 (1.03–1.16) 0.005    1.09 (1.05–1.13) 0.0004   
eGFR 0.46 (0.32–0.66) 0.0001 0.20 (0.05–0.86) 0.031 0.32 (0.23–0.48) <0.0001   
Hs–CRP 1.00 (0.99–1.01) 0.713    1.01 (1.00–1.01) 0.013   
White blood cell 1.02 (0.99–1.05) 0.148    1.01 (0.97–1.05) 0.653   
Red blood cell 0.84 (0.73–0.97) 0.017    0.88 (0.73–1.04) 0.158   
Hemoglobin 0.93 (0.89–0.98) 0.004    0.95 (0.89–1.02) 0.143   
Hematocrit 0.98 (0.96–0.99) 0.003    0.98 (0.95–1.00) 0.073   
MCV 1.00 (0.98–1.01) 0.656    1.02 (1.00–1.04) 0.047   
MCH 0.97 (0.94–1.01) 0.099    1.00 (0.97–1.01) 0.687   
MCHC 0.91 (0.84–0.99) 0.029    0.89 (0.81–0.98) 0.016   
  1. PCI, percutaneous coronary intervention; HR, hazard ratio; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular-hemoglobin concentration. eGFR = estimated glomerular filtration rate calculated by the chronic kidney disease-EPI two-level race equation [12]