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Table 3 Cox proportional hazard model of baseline clinical risk factors for the development of major adverse cardiovascular events stratified by acute coronary syndrome and elective PCI subjects

From: The burden of major adverse cardiac events in patients with coronary artery disease

 

Acute coronary syndrome

Elective PCI

Baseline data

Univariate analysis HR (95% CI)

P value

Multivariate model HR (95% CI)

P value

Univariate

analysis HR

(95% CI)

P value

Multivariate model HR (95% CI)

P value

Age

1.02 (1.02–1.03)

<0.0001

  

1.03 (1.01–1.04)

<0.0001

  

Gender

1.10 (0.85–1.45)

0.486

  

1.15 (0.88–1.54)

0.317

  

Education (illiterate)

1.63 (1.19–2.18)

0.002

  

1.25 (0.85–1.79)

0.257

  

Marital status (widow or widower)

1.44 (1.02–1.98)

0.040

  

0.90 (0.55–1.40)

0.662

  

Malnourished

2.87 (0.86–7.21)

0.082

  

4.00 (1.20–9.91)

0.027

  

Economic situation (dependent)

1.52 (1.18–1.97)

0.001

  

1.81 (1.34–2.45)

0.0001

  

Smoking

1.11 (0.89–1.39)

0.369

  

0.98 (0.76–1.26)

0.857

  

Drinking

0.90 (0.68–1.17)

0.414

  

0.97 (0.71–1.31)

0.849

  

Regular exercise

0.85 (0.65–1.11)

0.236

  

0.79 (0.57–1.07)

0.127

  

Antihypertensive medication

0.98 (0.78–1.24)

0.885

  

0.95 (0.73–1.22)

0.661

  

Statins

0.87 (0.69–1.09)

0.222

  

0.98 (0.74–1.29)

0.909

  

Hypoglycemic medication

1.17 (0.89–1.53)

0.262

  

1.43 (1.01–1.98)

0.042

  

Triple vessel disease

1.67 (1.33–2.10)

<0.0001

3.66 (1.38–9.97)

0.009

2.27 (1.75–2.93)

<0.0001

3.12 (1.43–6.82)

0.005

Stent implantation

1.50 (1.18–1.90)

0.001

3.61 (1.47–9.05)

0.005

1.47 (1.12–1.91)

0.005

4.10 (2.09–8.13)

0.0001

Anemia

1.42 (1.10–1.81)

0.007

  

1.47 (1.09–1.95)

0.011

  

Diabetes mellitus

1.78 (1.42–2.23)

<0.0001

  

1.35 (1.04–1.74)

0.024

  

Hypertension

1.27 (0.97–1.67)

0.079

1.73 (1.06–2.21)

0.020

1.50 (1.11–2.07)

0.008

1.07 (1.02–2.37)

0.014

Hyperlipidemia

0.99 (0.78-1.28)

0.960

  

1.03 (0.79-1.34)

0.839

  
  1. HR Hazard ratio, PCI percutaneous coronary intervention