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Table 4 Base-case results: Pairwise comparison

From: Use of low density lipoprotein particle number levels as an aid in statin treatment decisions for intermediate risk patients: a cost-effectiveness analysis

 

Test-and-MST

Do-not-treat

Increment

Test-and-HST

MST

Increment

CVD events (n)

3787

3884

(97)

3177

3311

(134)

RVSC events (n)

3197

3294

(97)

2646

2727

(81)

Mild Adverse Events (n)

560

0

560

5600

5600

0

Severe Adverse Events (n)

4

0

4

37

37

0

Diabetes diagnoses (n)

36

0

36

442

368

74

Cost ($, Millions)

336.63

339.88

(3.25)

298.55

303.22

(4.67)

QALYs

460,162

460,118

44

460,119

460,004

115

  1. Care strategies: do-not-treat, no statin therapy; test-and-MST, moderate-intensity statin therapy for those in the top decile of LDL-P levels; MST, moderate-intensity statin therapy for all; test-and-HST, high-intensity statin therapy those in the top decile of LDL-P levels and moderate-intensity statin therapy for all other; HST, high-intensity statin therapy for all
  2. CVD cardiovascular disease, RVSC revascularization