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Table 4 Ovid MEDLINE and EMBASE search strategy

From: Mineralocorticoid receptor antagonists for heart failure: systematic review and meta-analysis

1

Exp heart failure/

376335/94836

2

Exp Cardiomyopathy/

113241/78224

3

Exp Ventricular dysfunction/

13819/28965

4

((heart or cardiac or myocardial) adj2 (failure or decompensation)).ti,ab

211838/130125

5

((congestive or chronic) adj2 heart failure).ti,ab

67554/45613

6

((ventric$) adj2 (failure or insufficien$ or dysfunction$ or function$)).ti,ab

82523/54772

7

((Reduced or preserved) adj2 "ejection fraction").ti,ab.

6293/2856

8

(HFpEF or HFrEF).mp

2216/776

9

((diastol$ or systol$) adj2 ((failure or dysfunction$ or function$)).ti,ab

48968/27523

10

Or/1-9

538115/275995

11

(animal$ not (human$ and animal$)).sh,hw.

3987846/4137327

12

10 NOT 11

501141/241626

13

exp Aldosterone Antagonist/

32899/8124

14

(eplerenone or inspra or spironolactone or aldactone or aldo$ or mineralocorticoid receptor antagon$ or canren$ or fineren$). ti,ab

134477/63667

15

(aldosterone adj2 antagon$). ti,ab

7857/2066

16

Or/13-15

134563/63667

17

16 NOT 11

111915/46794

18

12 and 17

20116/4880

19

(1995* or 1996* or 1997* or 1998* or 1999* or 2000* or 2001* or 2002* or 2003* or 2004* or 2005* or 2006* or 2007* or 2008* or 2009* or 2010* or 2011* or 2012* or 2013* or 2014* or 2015* or 2016*).dd

21741062/0

20

(1995* or 1996* or 1997* or 1998* or 1999* or 2000* or 2001* or 2002* or 2003* or 2004* or 2005* or 2006* or 2007* or 2008* or 2009* or 2010* or 2011* or 2012* or 2013* or 2014* or 2015* or 2016*).ed

0/16309819

21

19 or 20

21741062/16309819

22

18 AND 21

17787/3735

23

(book or conference paper or editorial or letter or review).pt. not exp randomized controlled trial/

4298634/3319843

24

(random sampl$ or random digit$ or random effect$ or random survey or random regression).ti,ab. not exp randomized controlled trial/

69917/56001

25

(random$ or placebo$ or single blind$ or double blind$ or triple blind$).ti,ab.

1177770/884750

26

25 not (23 or 24 or 11)

908857/648772

27

22 and 26

1802/503 = 2305

28

Remove duplicates from 27

1372/502 = 1874

  1. (Search performed January 29, 2016)