Table 3 Association between UA level and all-cause mortality, CVE mortality and CVE event in the subcohort with multiple UA measures and without history of CVE at baseline

 UA^b

1.17 (1.01,1.36)

0.031

1.17 (0.98,1.40)

0.082

 UA z-score^b

1.13 (1.00,1.27)

0.040

1.13 (0.98,1.30)

0.097

 UA category

0.636

0.906

  Low

1.00

1.00

  Medium

1.07 (0.83,1.36)

0.609

1.03 (0.79,1.34)

0.833

  High

1.18 (0.84,1.67)

0.343

1.09 (0.73,1.64)

0.658

 Average UA z-score^b

1.18 (1.02,1.36)

0.027

1.18 (1.00,1.39)

0.046

 Annual change UA z-score^c

1.14 (0.92,1.41)

0.220

1.11 (0.88,1.39)

0.379

 UA^b

1.18 (0.94,1.49)

0.152

1.10 (0.83,1.47)

0.507

 UA z-score^b

1.14 (0.94,1.37)

0.173

1.07 (0.85,1.35)

0.544

 UA category

0.838

0.977

  Low

1.00

1.00

  Medium

1.11 (0.75,1.63)

0.603

0.96 (0.63,1.46)

0.841

  High

1.15 (0.66,2.00)

0.622

0.98 (0.51,1.89)

0.962

 Average UA z-score^b

1.18 (0.93,1.49)

0.172

1.15 (0.88,1.49)

0.303

 Annual change UA z-score^c

1.21 (0.89,1.64)

0.219

1.10 (0.79,1.54)

0.573

 UA^b

1.25 (1.09,1.44)

0.001

1.09 (0.92,1.30)

0.300

 UA z-score^b

1.17 (1.05,1.31)

0.004

1.05 (0.92,1.20)

0.446

 UA category

0.032

0.848

  Low

1.00

1.00

  Medium

1.28 (1.01,1.63)

0.042

1.08 (0.83,1.40)

0.576

  High

1.52 (1.08,2.14)

0.015

1.09 (0.73,1.62)

0.668

 Average UA z-score^b

1.15 (1.00,1.31)

0.053

1.03 (0.88,1.20)

0.746

 Annual change UA z-score^c

1.31 (1.05,1.64)

0.017

1.11 (0.88,1.41)

0.384