Table 1 Characteristics of the full cohort by history of CVE at baseline
Characteristic or measure | CVE history = no (n = 3,475) | CVE history = yes (n = 698) |
|---|---|---|
Male gender (%) | 44.3 | 44.7 |
Age (years) | 47.8 (16.2) | 62.1 (14.5) |
Smoking | ||
 Never (%) | 53.6 | 49.4 |
 Ex (%) | 32.1 | 43.4 |
 Current (%) | 14.3 | 7.2 |
Alcohol | ||
 Never (%) | 6.8 | 7.2 |
 Ex (%) | 7.9 | 14.6 |
 Light (%) | 61.3 | 55.9 |
Mod/Heavy/Unknown (%) | 24.1 | 22.3 |
Physical activity (mins/week) | 275 (363) | 206 (306) |
Diet score (range 0 to 8) | 3.15 (1.51) | 3.35 (1.51) |
BMI (kg/m2) | 25.9 (4.1) | 26.6 (4.1) |
Systolic BP (mm Hg) | 122 (17) | 131 (21) |
Diastolic BP (mm Hg) | 74 (10) | 76 (11) |
Hypertension meds (%) | 11.3 | 44.4 |
Cholesterol (mmol/L) | 5.50 (1.09) | 5.82 (1.09) |
HDL (mmol/L) | 1.40 (0.38) | 1.37 (0.43) |
Triglycerides (mmol/L) | 1.24 (0.81) | 1.54 (1.22) |
Lipid meds (%) | 1.5 | 8.0 |
Diabetes (%) | 4.7 | 11.5 |
Gout history (%) | 1.4 | 3.6 |
Diuretic use (%) | 3.0 | 11.7 |
CRP (mg/L) | 2.97 (7.73) | 3.86 (10.21) |
MDRD eGFR (mL/min/1.73Â m2) | 72.3 (13.1) | 63.5 (14.4) |
UA (mmol/L) | 0.3108 (0.0806) | 0.3353 (0.0921) |
UA z-score | −0.0345 (0.9722) | 0.1173 (1.0649) |
UA categorya | ||
 Low (%) | 39.6 | 35.2 |
 Medium (%) | 51.1 | 48.3 |
 High (%) | 9.4 | 16.5 |
Outcomes | ||
Follow-up time (years) | 15.4 (2.6) | 13.6 (4.4) |
Deaths | 408 (11.7) | 244 (35.0) |
CVE deaths | 155 (4.5) | 118 (16.9) |
CVE events | 461 (13.3) | 301 (43.1) |