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Table 5 Risk of endomyocardial biopsy (EMB) complications reported in previous studies

From: Endomyocardial biopsy via the femoral access - still safe and valuable diagnostic tool

Author (year) Number of biopsies Overall complications rate (%) Major complications rate Minor complications rate Reference
Deckers (1992) 546 6 1.2a 4.8a [24]
Hiramitasu (1998) 19 964   0.7   [25]
Felker (1999) 323   0.32   [26]
Holzmann (2008) 3048 1.25a 0.1a 1.15a [12]
Yilmaz (2010) 622 (LVEMB) 3.5 (LVEMB) 0.6 (LVEMB) 2.9 (LVEMB) [13]
490 (RVEMB) 5.9 (RV EMB) 0.8 (RVEMB) 5.1 (RVEMB)
Huang (2010) 439 1.61 0.0 1.61 [27]
Saraiva (2011) 2217 0.71 - - [14]
Fiorelli (2012) 5347 6.2 0.3 5.9 [28]
Bennet (2013) 851 1.9 0.9 1.0 [16]
Jang (2013) 228 9.2 1.3 7.9 [15]
Chimenti (2013) 3549 (LVEMB) 2.33 (LVEMB) 0.33 (LVEMB) 2.0 (LVEMB) [22]
3068 (RVEMB) 1.8 (RVEMB) 0.45 (RVEMB) 1.35 (LVEMB)
Strecker (2013) 1896   1.0   [21]
Isogai (2015) 9508   0.98   [19]
Schulz (2015))~ 37 2.7 0 2.7 [1]
Schäufele (2015)~ 41 0 0 0 [23]
  1. avalues calculated on the basis of the manuscript data; LVEMB- left ventricle endomyocardial biopsy; RVEMB-right ventricle endomyocardial biopsy; ~ - transradial approach