Table 1 Baseline patients characteristics
From: Endomyocardial biopsy via the femoral access - still safe and valuable diagnostic tool
Baseline characteristics | All patients (n = 73) | HTx recipients (n = 32) | Other patients (n = 41) |
|---|---|---|---|
Age (years) | 47.6 ± 12.1 | 48.91 ± 11.24 | 40.02 ± 14.53 |
Sex | |||
Females | 16 | 9 | 7 |
Males | 57 | 23 | 32 |
BMI (kg/m2) | 24.37 ± 4.11 | 24.31 ± 3.99 | 24.05 ± 5.43 |
NYHA Class | |||
I, II, | 35 | 31 | 4 |
III, IV | 39 | 1 | 38 |
Coronary artery disease | 3 | 3 | 0 |
Myocardial infarction | 0 | 0 | 0 |
Hypertension | 11 | 11 | 0 |
Diabetes mellitus | 9 | 9 | 0 |
Prior pacemaker implantation | 2 | 2 | 0 |
Prior cardioverter-defibrilator implantation | 0 | 0 | 0 |
Prior cardiac resynchronisation therapy device implantation | 0 | 0 | 0 |
Prior rheumatic disease | 1 | 1 | 0 |
Renal failure | 14 | 9 | 5 |
GFR (ml/min/m2) | 71.66 ± 23.48 | 53.2 ± 23.16 | 72.83 ± 12.17 |
Blood pressure (mmHg) | |||
Systolic | 127.58 ± 15.29 | 129.89 ± 33.3 | 99.00 ± 12.04 |
Diastolic | 81.38 ± 11.23 | 82.95 ± 9.54 | 81.38 ± 11.23 |
Electrocardiogram | |||
Sinus rhytm | 70 | 30 | 42 |
Atrioventricular block | 0 | 0 | 0 |
Left Bundle Branch Block | 4 | 2 | 2 |
Right Bundle Branch Block | 6 | 6 | 0 |
Heart rate on admission (min−1) | 95.26 ± 13.48 | 95.98 ± 13.37 | 84.60 ± 12.18 |
PQ-interval (s) | 0.147 ± 0.043 | 0.160 ± 0.06 | 0.14 ± 0.06 |
QRS-width (s) | 0.119 ± 0.022 | 0.120 ± 0.06 | 0.18 ± 0.018 |
QT-interval (s) | 0.36 ± 0.32 | 0.38 ± 0.14 | 0.36 ± 0.50 |
ST-segment alterations | 5 | 2 | 3 |
Negative T-wave | 5 | 2 | 3 |
Cardiac Biomarkers | |||
Creatine kinase (U/L) | 85.78 ± 82.17 | 38.26 ± 75.68 | 187.00 ± 192.85 |
Creatine kinase- MB (U/L) | 21.44 ± 8.64 | 21.27 ± 8.86 | 16.2 ± 15.81 |
Troponin I (ng/mL) | 0.37 ± 1.67 | 0.23 ± 0.97 | 4.51 ± 2.75 |
Brain natriuretic peptide (pg/mL) | 312.08 ± 365.13 | 261.13 ± 284.35 | 948.02 ± 641.85 |
Laboratory results on admission | |||
C-reactive protein (mg/L) | 32.29 ± 8.72 | 12.21 ± 34.35 | 47.18 ± 62.20 |
Hemoglobin concentatration (mmol/L) | 7.8 ± 1.2 | 7.61 ± 1.04 | 10.35 ± 0.67 |
White blood cell count (1 × 109/L) | 6.47 ± 3.44 | 6.23 ± 3.19 | 10.23 ± 5.41 |
Platelets count (1 × 109/L) | 107.78 ± 57.27 | 205.13 ± 56.97 | 215.83 ± 55.42 |
Echocardiography | |||
Ejection fraction (%) | 61.24 ± 14.65 | 64.32 ± 8.92 | 17.67 ± 5.16 |
Left ventricle end diastolic diameter (mm) | 45.92 ± 14.65 | 44.41 ± 4.58 | 68.33 ± 10.04 |
Interventricular septum (mm) | 11.9 ± 2.14 | 12.00 ± 2.07 | 9.91 ± 2.20 |
Posterior wall (mm) | 11.38 ± 2.73 | 11.42 ± 2.73 | 10.75 ± 2.98 |
Right ventricle end diastolic diameter (mm) | 28.19 ± 4.23 | 27.98 ± 4.13 | 32.00 ± 4.20 |
Right ventricular systolic pressure (mmHg) | 32.39 ± 8.72 | 32.27 ± 9.00 | 33.25 ± 4.71 |
Pericardial effusion | |||
< 4 mm | 6 | 4 | 2 |
> 4 mm | 0 | 0 | 0 |
Tricuspid valve dysfunction | |||
Mild | 5 | 5 | 2 |
Moderate | 3 | 1 | 6 |
Severe | 0 | 0 | 2 |
Cardiac catheterization | |||
Right atrial pressure (mmHg) | |||
Systolic | 14.00 ± 7.18 | 12.00 ± 6.00 | 16.00 ± 9.00 |
Diastolic | 8.00 ± 5.30 | 6.00 ± 3.50 | 10.00 ± 7.00 |
Mean | 11 ± 6.14 | 8.00 ± 2.70 | 14.00 ± 8.00 |
Right ventricular pressure (mmHg) | |||
Systolic | 39.2 ± 17.73 | 27.00 ± 6.00 | 51.00 ± 18.4 |
Diastolic | 7.33 ± 8.55 | 6.00 ± 4.00 | 8.00 ± 9.00 |
End diastolic | 10 ± 6.83 | 4.00 ± 5.50 | 15.00 ± 5.00 |
Pulmonary Artery Pressure (mmHg) | |||
Systolic | 31.00 ± 11.64 | 24.00 ± 7.00 | 39.00 ± 11.00 |
Diastolic | 16.33 ± 9.91 | 12.00 ± 5.00 | 20.00 ± 13.00 |
Mean | 19.30 ± 13.70 | 15 ± 7.00 | 30.00 ± 16.50 |