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Table 5 Association of the VEGFA genotype with the Gensini score after adjustment for clinical variables

From: The association of functional polymorphisms in genes encoding growth factors for endothelial cells and smooth muscle cells with the severity of coronary artery disease

Gene /polymorphism Dominant Model* (mean Gensini score ± standard error) P Recessive Model* (mean Gensini score ± standard error) P Log additive model* P
  Genotypes   Genotype   Difference in Gensini score per minor allele (95 % CI)  
  A/A (ref.) A/C + C/C   A/A + A/C (ref.) C/C   Per C allele  
  Whole cohort
VEGFA
rs699947
37.9 ± 3.2 35.6 ± 1.9 0.57 37.9 ± 2.0 31.6 ± 2.7 0.22 −2.3 (−6.4 ÷ 1.9) 0.28
  Patients without previous myocardial infarction
VEGFA
rs699947
26.4 ± 2.4 35.1 ± 2.1 0.04 31.4 ± 2.0 35.5 ± 3.3 0.41 3.8 (−0.51 ÷ 8.0) 0.09
  1. *The models were adjusted for: age, sex, hypertension, atrial fibrillation, diabetes mellitus, previous myocardial infarction and creatinine