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Table 4 Characteristics of patients with definite and probable stent thrombosis

From: High platelet reactivity affects the clinical outcomes of patients undergoing percutaneous coronary intervention

Case

Risk factors

Lesions

Stent number

AA-MAR, %

ADP-MAR, %

CYP2C19 gene

Use of antiplatelet drugs

Time from PCI to stent thrombosis (days)

Cardiac death

1

EH

Multi-vessel disease

2

15.4

60.6

NA

Dual-antiplatelet for 2 years

2

0

2

Smoking

Left main lesion

3

42.9

60.3

NA

Dual-antiplatelet for 2 years

241

1

3

EH, DM, smoking

Multi-vessel disease

8

35

58.4

Poor metabolizer

Dual-antiplatelet for 2 years

170

0

4

EH, smoking

Multi-vessel disease

3

20

58.6

NA

Dual-antiplatelet for 2 years

1

0

5

DM

Multi-vessel disease

3

79.8

67.9

NA

Clopidogrel for lifelong time, aspirin for half year

236

1

6

EH, smoking

Pro-LAD lesion

1

50

60.5

Intermediate metabolizer

Clopidogrel for 1 year, aspirin stopped by oneself at 1 month after procedure, and aspirin re-used at 1 year

455

0

7

EH

Multi-vessel disease

3

20.2

63

Intermediate metabolizer

Aspirin for lifelong time, clopidogrel for 1 year

12

0

8

EH, DM

Multi-vessel disease

2

39

58.7

Intermediate metabolizer

Dual-antiplatelet for 2 years

82

0

9

No

Multi-vessel disease + left main lesion

3

49.8

61.1

NA

Dual-antiplatelet for 2 years

94

1

10

EH, DM

Multi-vessel disease + left main lesion

6

37

45

Poor metabolizer

Dual-antiplatelet for 2 years

1

0

11

DM, smoking

Multi-vessel disease

4

24.6

56.4

Poor metabolizer

Dual-antiplatelet for 2 years

731

1

12

EH, DM, smoking, CKD 4

Multi-vessel disease + left main lesion

7

21.1

68

Intermediate metabolizer

Dual-antiplatelet for 2 years

617

1

13

Smoking

Multi-vessel disease

2

34.6

57.2

Intermediate metabolizer

Dual-antiplatelet for 2 years

42

1

14

EH

Multi-vessel disease

6

45.4

60.3

Intermediate metabolizer

Dual-antiplatelet for 2 years

138

1

  1. EH essential hypertension, DM diabetes mellitus, CKD chronic kidney disease, LAD left anterior descending, AA arachidonic acid, MAR maximal aggregation ratio, ADP adenosine diphosphate, PCI percutaneous coronary intervention