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Table 1 Baseline clinical characteristics

From: High platelet reactivity affects the clinical outcomes of patients undergoing percutaneous coronary intervention

  NPR on aspirin (n = 1240) HPR on aspirin (n = 91) P value NPR on clopidogrel (n = 891) HPR on clopidogrel (n = 437) P value
Age, yrs 64.19 ± 10.06 65.63 ± 9.75 0.189 63.96 ± 10.23 64.98 ± 9.60 0.082
Male, n (%) 936 (75.5) 67 (73.6) 0.706 692 (77.7) 310 (70.9) 0.008
BMI, kg/mm2 24.70 ± 3.01 24.55 ± 3.01 0.649 24.65 ± 2.95 24.78 ± 3.12 0.449
Hypertension, n (%) 888 (71.6) 66 (72.5) 0.905 644 (72.3) 307 (70.3) 0.438
Hyperlipidemia, n (%) 318 (27.4) 23 (25.6) 0.806 236 (28.3) 105 (25.4) 0.281
Diabetes, n (%) 328 (26.5) 24 (26.4) NS 239 (26.8) 112 (25.6) 0.691
Current smoking, n (%) 482 (39.2) 33 (36.7) 0.656 356 (40.3) 159 (36.7) 0.229
ACS, n (%) 1072 (86.5) 75 (82.4) 0.272 782 (87.8) 362 (82.8) 0.018
eGFR < 60 ml/min/1.73 m2, n (%) 122 (10.1) 8 (9.2) NS 94 (10.9) 36 (8.4) 0.170
Prior stroke, n (%) 138 (11.2) 11 (12.2) 0.731 93 (10.5) 56 (12.9) 0.196
Prior PCI, n (%) 236 (19.2) 15 (16.7) 0.676 161 (18.2) 89 (20.6) 0.331
LVEF, % 59.80 ± 9.33 58.50 ± 9.89 0.275 59.59 ± 9.27 59.94 ± 9.61 0.587
hsCRP, ug/ml 31.94 ± 8.88 32.84 ± 9.16 0.400 31.98 ± 8.80 32.13 ± 9.11 0.804
Agents in hospital
 Aspirin, 100 mg/d 1216 (98.1) 90 (98.9) NS 881 (98.9) 428 (97.9) 0.218
 Clopidogrel, 75 mg/d 1203 (97.0) 88 (96.7) 0.751 863 (96.9) 426 (97.5) 0.606
Agents at 2 years
 Aspirin (100 mg/d), n (%) 1142 (92.1) 81 (89.0) 0.317 800 (89.8) 398 (91.1) 0.493
 Clopidogrel (75 mg/d), n (%) 806 (65.0) 57 (62.6) 0.650 570 (64.0) 266 (61.9) 0.277
  1. BMI body mass index, ACS acute coronary syndrome, eGFR estimated glomerular filtration rate, PCI percutaneous coronary intervention, LVEF left ventricular ejection fraction, hsCRP high sensitivity C reactive protein, NPR normal platelet reactivity, HPR high platelet reactivity