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Table 1 Baseline demographic and clinical characteristics of patients

From: Association between markers of glycemia and carotid intima-media thickness: the MARK study

 

Global (n = 427)

Diabetics (n = 92)

Non-Diabetics (n = 335)

p value

Age (years)

60.3 ± 8.5

59.7 ± 84.5

81.3 ± 113.4

0.483

Gender (women) n (%)

236 (55.3)

63 (68.5)

173 (51.6)

0.004

Smoker n (%)

82 (21.5)

19 (20.7)

73 (21.8)

0.887

Alcohol drinking (gr/week)

76.6 ± 108.1

60.9 ± 8.8

60.2 ± 8.4

0.089

METs/hour/week

3623 ± 3431

3378 ± 3153

3691 ± 3506

0.440

Body mass index (kg/m2)

28.3 ± 4.2

29.8 ± 5.0

27.9 ± 3.9

<0.001

Abdominal perimeter (cm)

97.5 ± 10.6

102.4 ± 11.7

96.2 ± 9.9

<0.001

Obesity patients n (%)

128 (27.6)

38 (41.3)

80 (23.9)

0.001

Office SBP (mmHg)

134 ± 17

137.0 ± 14.7

133.4 ± 17.1

0.067

Office DBP (mmHg)

81 ± 11

79.7 ± 10.1

81.5 ± 11.1

0.169

Office MBP (mmHg)

93 ± 10

93.4 ± 9.2

93.1 ± 9.7

0.783

Office Heart rate (bpm)

70 ± 11

73.0 ± 12.1

69.3 ± 10.8

0.005

Hypertensive patients n (%)

340 (79.6)

76 (82.6)

264 (78.8)

0.468

Antihypertensive Drugs n (%)

230 (53.9)

60 (65.2)

170 (50.7)

0.018

FPG (mg/dL)

97.9 ± 31.1

137.5 ± 46.1

87.0 ± 10.1

<0.001

Average PG (mg/dL)

120.2 ± 32.4

152.4 ± 9.5

111.3 ± 17.6

<0.001

HbA1c (%)

5.9 ± 1.0

7.2 ± 1.4

5.6 ± 0.3

<0.001

Diabetics patients n (%)

92 (21.5)

92 (21.5)

0 (0.0)

---

Antidiabetic drugs n (%)

76 (17.8)

76 (82.6)

0 (0.0)

---

Total Cholesterol (mg/dl)

215.0 ± 38.93

193.1 ± 41.1

221.0 ± 36.1

<0.001

LDL Cholesterol (mg/dl)

134.3 ± 34.5

113.4 ± 35.5

140.1 ± 32.0

<0.001

HDL-Cholesterol (mg/dl)

55.1 ± 14.3

51.6 ± 13.0

56.1 ± 14.5

0.009

Tryglicerides (mg/dl)

129.4 ± 92.6

149.0 ± 138.4

124.0 ± 74.8

0.022

No HDL-Cholesterol (mg/dl)

80.2 ± 13.8

79.8 ± 16.3

80.2 ± 13.0

0.805

Dyslipidemia patients n (%)

363 (85)

66 (71.7)

297 (88.7)

<0.001

Lipid lowering drugs n (%)

158 (37)

56 (60.9)

102 (30.4)

<0.001

Average mean IMT (mm)

0.738 ± 0.096

0.768 ± 0.111

0.729 ± 0.089

0.001

Carotid plaques n (%)

75 (17.6)

28 (30.4)

47 (14.1)

<0.001

TOD carotid n (%)

77 (18.0)

29 (31.5)

48 (14.3)

<0.001

Average maxima IMT (mm)

0.906 ± 0.117

0.942 ± 0.136

0.896 ± 0.109

0.001

  1. Values are means and standard deviations (SD) for distributed continuous data, and absolute frequencies and percentages (%) for categorical data
  2. METs metabolic equivalents, SBP systolic blood pressure, DBP diastolic blood pressure, MBP mean blood pressure, FPG fasting plasma glucose, PG postprandial glucose, HbA1c glycosylated hemoglobin, LDL low density lipoprotein, HDL high density lipoprotein, IMT intima-media thickness of common carotid artery, TOD target organ damage
  3. No HDL-Cholesterol mg/dl = (Total Cholesterol – HDL Cholesterol)
  4. TOD = Plaque or carotid IMT >0.90 mm