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Table 3 Receiver-operating analysis for heart failure biomarkers

From: Serum insulin-like growth factor-1 and its binding protein-7: potential novel biomarkers for heart failure with preserved ejection fraction

Biomarker

 

AUC

Std. Error

95%CI

p-value

IGF-1 (ng/ml)

0.694

0.046

0.605-0.783

< 0.001

IGFBP-7 (ng/ml)

0.730

0.044

0.643-0.817

< 0.001

IGFBP7/IGF-1

0.785

0.039

0.708-0.862

< 0.001

NT-proBNP (pg/ml)

0.835

0.036

0.765-0.905

< 0.001

  1. Diagnostic performance of biomarkers for the diagnosis of HFpEF in the subgroup of patients with HFpEF and controls. IGF-1 insulin-like growth factor-1; IGFBP-7 insulin-like growth factor binding protein-7. CI confidence interval. T-proBNP, N-terminal pro-B natriuretic peptide