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Table 2 IGF-1, IGFBP7 and IGFBP-7/IGF-1 ratio (n = 300)

From: Serum insulin-like growth factor-1 and its binding protein-7: potential novel biomarkers for heart failure with preserved ejection fraction

Biomarker

Controls (n = 55)

LVDD (n = 168)

HFpEF (n = 77)

Median [IQ range]

Range

Median [IQ range]

Range

Median [IQ range]

Range

IGF-1 (ng/ml)

120.00 [100.80-144.00]

61.60-217.50

112.30 [88.80-137.10]

42.20-216.40

99.50 [72.20-124.40]

21.80-191.60

IGFBP-7 (ng/ml)

50.30 [43.10-55.30]

30.80-79.80

54.40 [48.15-63.40]

30.20-115.80

61.10 [51.60-69.70]

32.90-177.6

IGFBP7/IGF-1

0.43 [0.33-0.56]

0.019-0.87

0.48 [0.38-0.66]

0.19-1.50

0.68 [0.50-0.88]

0.22-3.20

  1. IGF-1 insulin-like growth factor-1; IGFBP-7 insulin-like growth factor binding protein-7. We used the Kruskal-Wallis to test the equality of medians among more than two distinct groups