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Table 2 IGF-1, IGFBP7 and IGFBP-7/IGF-1 ratio (n = 300)

From: Serum insulin-like growth factor-1 and its binding protein-7: potential novel biomarkers for heart failure with preserved ejection fraction

Biomarker Controls (n = 55) LVDD (n = 168) HFpEF (n = 77)
Median [IQ range] Range Median [IQ range] Range Median [IQ range] Range
IGF-1 (ng/ml) 120.00 [100.80-144.00] 61.60-217.50 112.30 [88.80-137.10] 42.20-216.40 99.50 [72.20-124.40] 21.80-191.60
IGFBP-7 (ng/ml) 50.30 [43.10-55.30] 30.80-79.80 54.40 [48.15-63.40] 30.20-115.80 61.10 [51.60-69.70] 32.90-177.6
IGFBP7/IGF-1 0.43 [0.33-0.56] 0.019-0.87 0.48 [0.38-0.66] 0.19-1.50 0.68 [0.50-0.88] 0.22-3.20
  1. IGF-1 insulin-like growth factor-1; IGFBP-7 insulin-like growth factor binding protein-7. We used the Kruskal-Wallis to test the equality of medians among more than two distinct groups