Characteristics | Treatment group | ||
---|---|---|---|
Hydrochlorothiazide + amiloride | Atenolol | Placebo | |
Number of patients enrolled | 1081 (24.6) | 1102 (25.1) | 2213 (50.3) |
Male, n (%) | 454 (42.0) | 456 (41.4) | 926 (41.8) |
Age, years | 70.4 ± 2.7 | 70.3 ± 2.8 | 70.3 ± 2.7 |
Weight, kg | 70.1 ± 12.4 | 70.4 ± 12.5 | 70.0 ± 12.6 |
Serum potassium, mmol/L‡ | 4.2 ± 0.4 (n = 1046) | 4.2 ± 0.4 (n = 1072) | 4.2 ± 0.4 (n = 2160) |
Serum sodium, mmol/L‡ | 141.6 ± 2.0 (n = 1055) | 141.6 ± 2.0 (n = 1083) | 141.6 ± 2.0 (n = 2173) |
Glucose, mmol/L‡ | 3.4 ± 0.7 (n = 999) | 3.4 ± 0.7 (n = 1025) | 3.4 ± 0.7 (n = 2051) |
Serum cholesterol, mmol/L‡ | 6.5 ± 1.3 (n = 1054) | 6.5 ± 1.2 (n = 1075) | 6.4 ± 1.2 (n = 2154) |
Serum urea, mmol/L‡ | 6.0 ± 1.4 (n = 1036) | 5.9 ± 1.4 (n = 1066) | 5.9 ± 1.3 (n = 2128) |
Serum urate, μmol/L‡ | 341.8 ± 70.5 (n = 1002) | 336.8 ± 71.4 (n = 1030) | 337.8 ± 70.5 (n = 2053) |