Fig. 2

Example illustrating the modified calculator with customizable uncertainty limits for a white female with baseline calculated ten-year risk of 3.5 %. The uncertainty in the measurement values of age, total-c, HDL-c and BP can be input using this customizable tool. The blue bar depicts the calculated baseline ten-year risk, and the red bar represents the maximum and minimum risk. In the depicted example, maximum and minimum risks were computed by assuming variations in input of age (0–1 year) and ± 10 % variation in total-cholesterol (c), HDL-c, and systolic blood pressure. Boundary limits of 5 % and 7.5 % are marked by dashed and solid line, respectively. Our version of the risk calculator is available online [18]