Fig. 2

Shows the Tornado diagram with parameters having the greatest impact on the top. The gray dotted line was the ICER value (US$6,298) of LAA occlusion compared to warfarin with base-case result. The all-cause mortalities of warfarin (variable range: 0.5 to 4.13 %) and LAA occlusion (variable range: 1.8 to 2.7 %) had the greatest impact in the model. Even though the range of ICER values of the two parameters were not greater than the threshold of US$50,000, both parameters could still affect the results in the model. The other parameters assessed were not sensitive to the model’s outcomes