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Table 2 Demographics and baseline characteristics of Chronic Heart Failure patients according to cognitive function (CI) n = 525

From: Ischemic aetiology, self-reported frailty, and gender with respect to cognitive impairment in chronic heart failure patients

 

Overall

Normal

Cognitive impairment

n

p value

Demographics, n%

525

380 (72)

145 (28)

525

 

Age, years, mean (SD)

71 (11)

70 (11)

75 (9)

525

<0.001

Female gender n (%)

205 (39)

126 (33)

79 (55)

525

<0.001

NYHA class n% (I, II / III, IV)

300 (59) / 211 (41)

229 (62) / 139 (38)

71 (50) / 72 (50)

511

0.007

Heart rate > =70, bpm, n (%)

304 (59)

210 (56)

94 (66)

515

0.034

SBP, mean (SD)

126 (22)

126 (23)

124 (21)

517

0.324

Preserved LVEF %, mean (SD)

180 (34)

131 (34)

49 (34)

525

0.484

Aetiology of CHF, n%

382 (73)

268 (71)

114 (79)

520

0.042

Hypertension n%

412 (79)

295 (79)

114 (79)

520

0.459

Diabetes n%

239 (47)

162 (44)

77 (54)

511

0.023

Peripheral artery disease n%

99 (19)

63 (17)

36 (25)

521

0.020

CKD

286 (55)

195 (52)

91 (63)

523

0.014

Anaemia n%

176 (33)

120 (32)

56 (39)

525

0.078

Cerebrovascular disease n%

62 (12)

40 (11)

22 (15)

521

0.089

COPD n%

114 (22)

79 (21)

35 (24)

517

0.239

ACEI or ARBs n%

426 (82)

311 (83)

115 (80)

519

0.243

Betablockers n%

482 (92)

358 (95)

124 (86)

522

0.001

MRA n%

228 (44)

167 (44)

61 (42)

521

0.383

Nt-pro BNP n%

248 (48)

169 (45)

79 (56)

515

0.014

Albumin mean (SD)

4 (0)

4 (0)

3.6 (0)

501

<0.001

Albumin < 3.5

97 (19)

57 (16)

40 (28)

501

0.002

eGFR mean (SD)

59 (22)

60 (23)

55 (21)

523

<0.017

  1. Cognitive impairment defined by age and education corrected MMSE scores. Data are presented as means ± standard deviation, medians (with interquartil range) or numbers (with percentages) where appropriate. Percentages are rounded. NYHA class: New York Heart Association functional class: LVEF: left ventricle ejection fraction. SBP: systolic blood pressure. CHF: chronic heart failure. Aetiology of CHF: patients with ischemic and hypertensive aetiology versus other causes. CKD: Chronic kidney Disease: eGFR < 60 mL/min/1.73 m2. Anaemia was defined as haemoglobin level <12 g/dL in women and <13 gr/dL in men. Cerebrovascular disease defined as. COPD: chronic obstructive pulmonary disease defined following GOLD (Global Initiative of Chronic Obstructive Lung disease) Guidelines. ACEI:angiotensin-converting-enzyme inhibitor. ARBs: Angiotensin II receptor blockers. MRA: Mineral corticoid receptor blockers. Nt-proBNP: N-terminal pro Brain Natriuretic Peptide over 1512 (median scores). eGFR: estimated glomerular filtration rate