Table 1 Patient demographics and baseline characteristics of the study cohort, and three sets of cases and controls
Study cohort | Hemorrhagic stroke | UGIB | LGIB | |||||
|---|---|---|---|---|---|---|---|---|
(N = 27,707) | Cases (n = 70) | Controls (n = 1,000) | Cases (n = 152) | Controls (n = 1,000) | Cases (n = 316) | Controls (n = 2,000) | ||
Sex | Male | 18,887 (68.2) | 45 (64.3) | 668 (66.8) | 102 (67.1) | 681 (68.1) | 191 (60.4) | 1,369 (68.5) |
Female | 8,820 (31.8) | 25 (35.7) | 332 (33.2) | 50 (32.9) | 319 (31.9) | 125 (39.6) | 631 (31.6) | |
Age, years | 50–59 | 5,929 (21.4) | 5 (7.1) | 59 (5.9) | 13 (8.6) | 75 (7.5) | 30 (9.5) | 241 (12.1) |
60–69 | 9,323 (33.6) | 16 (22.9) | 237 (23.7) | 41 (27.0) | 277 (27.7) | 82 (25.9) | 621 (31.1) | |
70–79 | 9,545 (34.4) | 30 (42.9) | 456 (45.6) | 66 (43.4) | 436 (43.6) | 144 (45.6) | 832 (41.6) | |
80–84 | 2,910 (10.5) | 19 (27.1) | 248 (24.8) | 32 (21.1) | 212 (21.2) | 60 (19.0) | 306 (15.3) | |
BMI, kg/m2 | <20 | 632 (2.3) | 6 (8.6) | 35 (3.5) | 6 (3.9) | 22 (2.2) | 10 (3.2) | 61 (3.0) |
20–24 | 6,419 (23.2) | 17 (24.3) | 249 (24.9) | 36 (23.7) | 246 (24.6) | 65 (20.6) | 441 (22.1) | |
25–29 | 10,645 (38.4) | 21 (30.0) | 413 (41.3) | 64 (42.1) | 414 (41.4) | 139 (44.0) | 868 (43.4) | |
≥30 | 6,328 (22.8) | 21 (30.0) | 258 (25.8) | 39 (25.7) | 284 (28.4) | 89 (28.2) | 546 (27.3) | |
Unknown | 3,683 (13.3) | 5 (7.1) | 45 (4.5) | 7 (4.6) | 34 (3.4) | 13 (4.1) | 84 (4.2) | |
History of peptic ulcer diseasea | None | 25,077 (90.5) | 56 (80.0) | 867 (86.7) | 109 (71.7) | 876 (87.6) | 277 (87.7) | 1,824 (91.2) |
Uncomplicated | 1,615 (5.8) | 11 (15.7) | 96 (9.6) | 28 (18.4) | 97 (9.7) | 27 (8.5) | 119 (6.0) | |
Complicated | 1,015 (3.7) | 3 (4.3) | 37 (3.7) | 15 (9.9) | 27 (2.7) | 12 (3.8) | 57 (2.9) | |
Qualifying serious coronary event | Myocardial infarction | 16,107 (58.1) | 47 (67.1) | 586 (58.6) | 81 (53.3) | 587 (58.7) | 161 (50.9) | 1,110 (55.5) |
Unstable angina | 1,919 (6.9) | 4 (5.7) | 69 (6.9) | 14 (9.2) | 74 (7.4) | 36 (11.4) | 140 (7.0) | |
Elective revascularization | 9,681 (34.9) | 19 (27.1) | 345 (34.5) | 57 (37.5) | 339 (33.9) | 119 (37.7) | 750 (37.5) | |