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Table 7 Associations between renin levels and measures of atherosclerosis burden, arterial stiffness and endothelial function

From: Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes

  

T2D

  

RAASi

NoRAASi

ABPI

r

−0.19

−0.09

pCor

1.6E-05

ns

r2

0.14

0.16

pReg

3.6E-04

ns

CCA IMT

r

0.14

0.13

pCor

7.9E-04

0.021

r2

0.15

0.20

pReg

0.007

ns

Bulb IMT

r

0.26

0.29

pCor

1.0E-08

9.40E-07

r2

0.20

0.3

pReg

3.3E-05

0.029

Plaque area

r

0.26

0.20

pCor

7.7E-09

0.002

r2

0.26

0.29

pReg

3.2E-08

ns

PWV

r

0.02

0.09

pCor

ns

ns

r2

0.31

0.38

pReg

ns

ns

RHI

r

−0.16

−0.15

pCor

2.3E-04

0.007

r2

0.09

0.11

pReg

0.036

ns

  1. r is Pearson correlation coefficient, and r2 is proportion of variation explained by a linear regression model adjusted for age, gender, total cholesterol
  2. HDL systolic BP, smoking, eGFR, IL6, and study center
  3. RAASi RAAS inhibitor treatment