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Table 2 Odds-ratios for CVD risk with increased plasma renin levels (log2 scale)

From: Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes

Covariates All T2D Non-T2D
OR (95 % CI) p-value OR (95 % CI) p-value OR (95 % CI) p-value
Framingham (age, gender, total cholesterol, HDL, SBP, smoking) 1.37 (1.22–1.55) 9.5E-08 1.55 (1.34–1.80) 7.7E-09 1.45 (1.14–1.85) 3.0E-03
Framingham + eGFR 1.29 (1.14–1.45) 5.0E-05 1.42 (1.21–1.66) 1.2E-05 1.43 (1.12–1.83) 4.0E-03
Framingham + RAAS inhibitors 1.20 (1.06–1.36) 5.0E-03 1.41 (1.21–1.65) 1.3E-05 1.10 (0.84–1.44) ns
  1. P-values from separate logistic regression models adjusted for the individual components of the Framingham risk score and study center, and in addition for eGFR or RAAS inhibitors
  2. SBP systolic blood pressure, HDL high-density lipoprotein, eGFR estimated glomerular filtration rate