Table 1 Reported outcomes
Studies | Reported outcomes | Follow up period | Bias grade |
|---|---|---|---|
Brar2008 | Death, MI | 9.7Â months | - |
I-LOVE IT 2 | NACCE, death, MI, stroke, TVR, TLR, ST, all bleeding, major bleeding | 12 and 18Â months | B |
ISAR-SAFE | Primary endpoints, death, MI, ST, stroke, TIMI major and minor bleeding, BARC bleeding | 9Â months | B |
Tarantini2016 | Death, MI, composite endpoints, stent thrombosis, BARC type 3 or 5 bleeding, stroke, revascularization | 1Â year | - |
ARCTIC | Primary endpoints, Death, MI, ST, stroke, revascularization | 17Â months | B |
OPTIMIZE | NACCE, death, MI, stroke, ST, major bleeding, TLR, TVR, any bleeding | 1Â year | B |
RESET | Primary endpoints, death, MI, TVR, ST, major and minor bleeding, stroke | 1Â year | B |
EXCELLENT | Death, MI, stroke, TVR, TLR, ST, any bleeding, TIMI major bleeding | 1Â year | B |
PEGASUS | Death, MI, stroke, TIMI major and minor bleeding | 3Â years | B |
DAPT | ST, MACCEs, death, stroke, MI, BARC type 2,3 or 5 | 12 to 30Â months | B |
Sardella2011 | Death, MI, stroke, TIMI minor bleeding, revascularization | 2Â years | - |
PRODIGY | Death, MI, stroke, ST, TLR, TVR, TIMI major and minor bleeding, BARC bleeding | 2Â years | B |
Thukkani2015 | Death, MI, Stroke | 4Â years | - |
ENDEAVOR | Death, MI, ST (definite and probable), stroke, major bleeding | 2Â years | B |
ITALIC | Primary endpoints, minor bleeding, minimal bleeding, death, MI, stroke, TVR, ST, major bleeding | 1Â year | B |