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Table 2 Relationships between the quartiles of HFABP and the incidence of AKI, levels of cardiac markers and in-hospital mortality

From: The serum heart-type fatty acid-binding protein (HFABP) levels can be used to detect the presence of acute kidney injury on admission in patients admitted to the non-surgical intensive care unit

 

Q1

Q2

Q3

Q4

 

H-FABP≦6.2 (n = 124)

6.3≦H-FABP≦11.6 (n = 123)

11.7≦H-FABP≦27.8 (n = 124)

27.9≦H-FABP (n = 123)

p value

Acute kidney injury

 no-AKI (yes, %)

113 (91.1 %)

102 (82.9 %)

90 (72.6 %)

44 (35.8 %)

<0.001

 Class R (yes, %)

9 (7.3 %)

16 (13.0 %)

23 (18.5 %)

35 (28.5 %)

<0.001

 Class I (yes, %)

1 (0.8 %)

5 (4.1 %)

6 (4.8 %)

24 (19.5 %)

<0.001

 Class F (yes, %)

1 (0.8 %)

0 (0.0 %)

5 (4.0 %)

20 (16.3 %)

<0.001

Biomarkers

 hs-TropT (ng/ml)

0.02 (0.01–0.03)

0.04 (0.02–0.06)

0.06 (0.03–0.10)

0.14 (0.06–0.54)

<0.001

 Nt-proBNP (pg/ml)

351 (68–1,748)

2,401 (925–5,451)

5,739 (1,991–13,267)

7929 (2,164–23,269)

<0.001

In-hospital mortality

 dead (yes, %)

3 (2.4 %)

5 (4.1 %)

18 (14.5 %)

38 (30.9 %)

<0.001

  1. H-FABP heart-type fatty acid binding, LVEF left ventricular ejection fraction measured on echocardiography; WBC white blood cell; BUN blood urea nitrogen, BS blood sugar, CRP C-reactive protein, BNP brain natriuretic peptide, hs-TropT high-sensitivity troponin T, Nt-proBNP N-Terminal pro-brain-type natriuretic peptide, hs-CRP high-sensitivity C-reactive protein, NPPV noninvasive positive pressure ventilation, ETI endotracheal intubation, IABP intra-aortic balloon pumping, PCPS percutaneous cardiopulmonary support, CHDF continuous hemodiafiltration, ICU intensive care unit
  2. p value between the quartiles of H-FABP determined using a variance analysis and the Kruskal-Wallis test