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Table 4 Clinical complications and outcome by age category and stratified by treatment strategy (n = 3475)

From: Predictors of non-invasive therapy and 28-day-case fatality in elderly compared to younger patients with acute myocardial infarction: an observational study from the MONICA/KORA Myocardial Infarction Registry

  Age category
Variable 25–64 years 65–74 years 75–84 years p Value
Treatment strategy All n = 1329 (100) IT n = 1187 (89.3) CT n = 142 (10.7) All n = 1083 (100) IT n = 891 (82.3) CT n = 192 (17.7) All n = 1063 (100) IT n = 683 (64.2) CT n = 380 (35.8) <0.0001
Complications during hospital stay  
 Cardiac arrest 76 (5.7) 58 (4.9) 18 (12.7) 110 (10.2) 79 (8.9) 31 (16.2) 176 (16.6) 102 (14.9) 74 (19.5) <0.0001
 Cardiogenic shock 54 (4.1) 48 (4.0) 6 (4.2) 77 (7.1) 66 (7.4) 11 (5.7) 101 (9.5) 75 (11.0) 26 (6.8) <0.0001
 Ventricular fibrillation 32 (2.4) 29 (2.4) 3 (2.1) 32 (3.0) 27 (3.0) 5 (2.6) 31 (2.9) 25 (3.7) 6 (1.6) 0.65
 Ventricular tachycardia 109 (8.2) 105 (8.9) 4 (2.8) 66 (6.1) 60 (6.7) 6 (3.1) 54 (5.1) 41 (6.0) 13 (3.4) 0.007
 Bradycardia 76 (5.7) 72 (6.1) 4 (2.8) 71 (6.6) 67 (7.5) 4 (2.1) 63 (5.9) 51 (7.5) 12 (3.2) 0.68
 Re-infarction 10 (0.8) 10 (0.8) 0 18 (1.7) 13 (1.5) 5 (2.6) 26 (2.5) 20 (2.9) 6 (1.6) 0.04
 Stroke 5 (0.4) 5 (0.4) 0 9 (0.8) 7 (0.8) 2 (1.0) 8 (0.8) 5 (0.7) 3 (0.8) 0.32
 Pulmonary edema 30 (2.3) 25 (2.1) 5 (3.5) 43 (4.0) 33 (3.7) 10 (5.2) 57 (5.4) 41 (6.0) 16 (4.2) 0.0003
 Any major bleeding complicationa 13 (1.0) 11 (0.9) 2 (1.4) 19 (1.8) 14 (1.6) 5 (2.6) 22 (2.1) 16 (2.3) 6 (1.6) 0.08
 Any in-hospital complication (without cardiac arrest) 254 (19.1) 236 (19.9) 18 (12.7) 243 (22.4) 208 (23.3) 35 (18.2) 249 (23.4) 185 (27.1) 64 (16.8) 0.02
Outcome
 28-day-case fatality 44 (3.3) 28 (2.4) 16 (11.3) 74 (6.8) 44 (4.9) 30 (15.6) 138 (13.0) 64 (9.4) 74 (19.5) <0.0001
 Death during hospital stay 43 (3.2) 28 (2.4) 15 (10.6) 74 (6.9) 45 (5.1) 30 (15.6) 146 (13.7) 72 (10.5) 74 (19.5) <0.0001
  1. Data are presented as number (percentage). P values were calculated for comparison of the age categories
  2. IT invasive therapy, CT conservative therapy
  3. a Major bleeding complication: intracranial or retroperitoneal or any other major spontaneous bleeding