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Table 6 Clinical characteristics and echocardiographic parameters of patients with chronic organic mitral regurgitation and the comparisons between subgroups of patients according to the symptom status and the severity of mitral regurgitation

From: Left atrial volume index as an independent determinant of pulmonary hypertension in patients with chronic organic mitral regurgitation

Variables

Total (N = 154)

Symptom status

Severity of MR

Symptomatic (N = 58)

Asymptomatic (N = 96)

P-value

Severe MR (N = 123)

Non-severe MR (N = 31)

P-value

Symptomatic

58 (37.7)

-

-

-

46 (37.4)

12 (38.7)

1.0

Severe MR

123(79.9)

46 (79.3)

77 (80.2)

1.0

-

-

-

Age (years)

55.0 ± 16.4

58.3 ± 16.2

53.0 ± 16.3

0.051

55.3 ± 16.1

53.9 ± 17.9

0.684

Male gender

93(60.4)

30(51.7)

63(65.6)

0.087

82(66.7)

11(35.5)

0.002

Atrial fibrillation

45(29.4)

25(43.1)

20(21.1)

0.004

34(27.9)

11(35.5)

0.406

LVDd (mm)

56.9 ± 6.6

57.7 ± 7.5

56.3 ± 5.9

0.245

58.3 ± 6.3

51.1 ± 4.1

<0.001

LVSd (mm)

33.8 ± 5.7

34.5 ± 6.3

33.4 ± 5.3

0.238

34.5 ± 5.8

31.0 ± 4.4

<0.001

LVEDV (ml)

113.3 ± 33.0

114.2 ± 36.4

112.8 ± 30.9

0.810

119.5 ± 32.3

89.0 ± 22.9

<0.001

LVESV (ml)

36.5 ± 13.6

37.8 ± 15.5

35.7 ± 12.3

0.382

38.0 ± 13.8

30.4 ± 10.5

0.005

LVMI (g/m2)

146.4 ± 43.44

163.8 ± 50.7

135.5 ± 34.3

<0.001

154.6 ± 42.5

113.3 ± 29.8

<0.001

E/E’

15.9 ± 6.1

18.0 ± 6.1

14.8 ± 5.9

0.002

16.6 ± 6.2

13.3 ± 5.0

0.008

TAPSE (mm)

22.7 ± 4.6

21.5 ± 4.6

23.4 ± 4.4

0.010

22.9 ± 4.5

22.0 ± 4.9

0.307

EROA (mm2)

61.8(22.0–250.9)

78.7(23.0–250.9)

56.5(22.0–225.1)

0.080

72.0(40.0–250.9)

28.9(22.0–44.9)

<0.001

RVol (ml)

102.1(20.3–336.2)

114.8(36.2–336.2)

95.5(20.3–267.9)

0.058

113.3(61.3–336.2)

48.1(20.3–75.0)

<0.001

LAV index (ml/m2)

67.1(24.7–391.3)

80.4(30.3–391.3)

62.5 (24.7–276.3)

0.007

71.7(30.3–391.3)

46.3(24.7–145.0)

<0.001

RVSP (mmHg)

43.2 ± 17.7

49.0 ± 18.0

39.6 ± 16.5

0.001

44.9 ± 18.7

36.3 ± 10.4

0.001

  1. Data are expressed as number (percentage), median (min-max) or mean ± standard deviation
  2. P-values are for comparisons between 2 groups
  3. E peak early diastolic velocity of mitral inflow, E’ tissue Doppler peak early diastolic velocity of medial mitral annulus, EROA effective regurgitant orifice area, LAV left atrial volume, LVDd left ventricular end-diastolic diameter, LVSd left ventricular end-systolic diameter, LVEDV left ventricular end-diastolic volume, LVESV left ventricular end-systolic volume, LVMI left ventricular mass index, MR mitral regurgitation, RVol regurgitant volume, RVSP right ventricular systolic pressure, TAPSE tricuspid annular plane systolic excursion