Variables | Total (N = 154) | Symptom status | Severity of MR | ||||
---|---|---|---|---|---|---|---|
Symptomatic (N = 58) | Asymptomatic (N = 96) | P-value | Severe MR (N = 123) | Non-severe MR (N = 31) | P-value | ||
Symptomatic | 58 (37.7) | - | - | - | 46 (37.4) | 12 (38.7) | 1.0 |
Severe MR | 123(79.9) | 46 (79.3) | 77 (80.2) | 1.0 | - | - | - |
Age (years) | 55.0 ± 16.4 | 58.3 ± 16.2 | 53.0 ± 16.3 | 0.051 | 55.3 ± 16.1 | 53.9 ± 17.9 | 0.684 |
Male gender | 93(60.4) | 30(51.7) | 63(65.6) | 0.087 | 82(66.7) | 11(35.5) | 0.002 |
Atrial fibrillation | 45(29.4) | 25(43.1) | 20(21.1) | 0.004 | 34(27.9) | 11(35.5) | 0.406 |
LVDd (mm) | 56.9 ± 6.6 | 57.7 ± 7.5 | 56.3 ± 5.9 | 0.245 | 58.3 ± 6.3 | 51.1 ± 4.1 | <0.001 |
LVSd (mm) | 33.8 ± 5.7 | 34.5 ± 6.3 | 33.4 ± 5.3 | 0.238 | 34.5 ± 5.8 | 31.0 ± 4.4 | <0.001 |
LVEDV (ml) | 113.3 ± 33.0 | 114.2 ± 36.4 | 112.8 ± 30.9 | 0.810 | 119.5 ± 32.3 | 89.0 ± 22.9 | <0.001 |
LVESV (ml) | 36.5 ± 13.6 | 37.8 ± 15.5 | 35.7 ± 12.3 | 0.382 | 38.0 ± 13.8 | 30.4 ± 10.5 | 0.005 |
LVMI (g/m2) | 146.4 ± 43.44 | 163.8 ± 50.7 | 135.5 ± 34.3 | <0.001 | 154.6 ± 42.5 | 113.3 ± 29.8 | <0.001 |
E/E’ | 15.9 ± 6.1 | 18.0 ± 6.1 | 14.8 ± 5.9 | 0.002 | 16.6 ± 6.2 | 13.3 ± 5.0 | 0.008 |
TAPSE (mm) | 22.7 ± 4.6 | 21.5 ± 4.6 | 23.4 ± 4.4 | 0.010 | 22.9 ± 4.5 | 22.0 ± 4.9 | 0.307 |
EROA (mm2) | 61.8(22.0–250.9) | 78.7(23.0–250.9) | 56.5(22.0–225.1) | 0.080 | 72.0(40.0–250.9) | 28.9(22.0–44.9) | <0.001 |
RVol (ml) | 102.1(20.3–336.2) | 114.8(36.2–336.2) | 95.5(20.3–267.9) | 0.058 | 113.3(61.3–336.2) | 48.1(20.3–75.0) | <0.001 |
LAV index (ml/m2) | 67.1(24.7–391.3) | 80.4(30.3–391.3) | 62.5 (24.7–276.3) | 0.007 | 71.7(30.3–391.3) | 46.3(24.7–145.0) | <0.001 |
RVSP (mmHg) | 43.2 ± 17.7 | 49.0 ± 18.0 | 39.6 ± 16.5 | 0.001 | 44.9 ± 18.7 | 36.3 ± 10.4 | 0.001 |