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Table 3 Baseline characteristics and echocardiographic parameters of patients with chronic organic mitral regurgitation and the comparisons between patients with and without pulmonary hypertension in the subgroups of patients with and without symptom

From: Left atrial volume index as an independent determinant of pulmonary hypertension in patients with chronic organic mitral regurgitation

 

Symptom (n = 58)

No symptom (n = 96)

Variables

No PH

PH

P-value

No PH

PH

P- value

 

(n = 34)

(n = 24)

 

(n = 79)

(n = 17)

 

Age (years)

59.3 ± 15.7

56.9 ± 17.1

0.580

50.9 ± 16.6

62.6 ± 10.6

0.001

Male gender

18(52.9)

12(50.0)

0.825

51(64.6)

12(70.6)

0.635

Hypertension

20(58.8)

9(37.5)

0.110

23(29.1)

9(52.9)

0.059

Diabetes mellitus

4(11.8)

1(4.2)

0.392

4(5.1)

1(5.9)

1.0

Dyslipidemia

16(47.1)

5(20.8)

0.041

17(21.5)

6(35.3)

0.228

Smoking

13(38.2)

6(25.0)

0.290

23(29.1)

4(23.5)

0.772

PAEDP (mmHg)

12.6 ± 4.8

21.0 ± 7.5

<0.001

11.3 ± 3.3

20.4 ± 8.0

<0.001

EROA (mm2)

51.0(23–251)

98.4(36–207)

0.001

56.1(22–162)

70.5(27–225)

0.250

RVol (ml)

106.3 ± 63.1

138.6 ± 54.1

0.047

96.0 ± 40.5

115.5 ± 55.6

0.096

Severe MR

24(70.6)

23(95.8)

0.019

62(78.5)

15(88.2)

0.510

LVEF (%)

68.2 ± 6.43

65.9 ± 6.0

0.169

68.6 ± 5.6

69.0 ± 5.9

0.782

LAV (ml)

93.3(50.5–286.8)

156.3(86.4–653.4)

0.001

97.2(44.5–486.3)

133.4(70.9–197.9)

0.002

LA index (ml/m2)

57.4(30.3–178.9)

98.0(54.3–391.3)

0.001

60.1(24.7–276.3)

74.1(42.0–114.1)

0.004

LA diameter (mm)

52.6 ± 8.7

63.1 ± 12.5

<0.001

48.9 ± 9.9

57.6 ± 8.0

0.001

LVDd (mm)

55.9 ± 7.2

60.2 ± 7.3

0.029

56.3 ± 6.3

56.7 ± 3.9

0.713

LVSd (mm)

32.9 ± 6.8

36.8 ± 4.7

0.018

33.5 ± 5.6

32.9 ± 4.1

0.669

LVEDV (ml)

104.7 ± 35.3

127.6 ± 34.2

0.017

112.6 ± 30.8

114.1 ± 32.3

0.855

LVESV (ml)

33.6 ± 15.3

43.8 ± 13.8

0.012

35.7 ± 12.2

35.8 ± 13.0

0.959

LVMI (g/m2)

155.6 ± 44.8

175.4 ± 56.9

0.144

132.3 ± 33.2

151.1 ± 36.5

0.046

E/E’

16.2 ± 5.7

21.0 ± 5.8

0.006

13.6 ± 5.0

20.4 ± 6.5

<0.001

TAPSE (mm)

22.2 ± 3.9

20.5 ± 5.4

0.183

23.7 ± 4.3

22.2 ± 4.4

0.185

St’ (cm/sec)

12.2 ± 2.2

11.4 ± 2.8

0.212

12.4 ± 1.9

12.1 ± 2.5

0.551

  1. Data are expressed as number (percentage), median (min-max) or mean ± standard deviation
  2. P-values are for comparisons between 2 groups
  3. A peak late diastolic velocity of mitral inflow, DT deceleration time, E peak early diastolic velocity of mitral inflow, E’ tissue Doppler peak early diastolic velocity of medial mitral annulus, EROA effective regurgitant orifice area, LA left atrium, LAV left atrial volume, LV left ventricle, LVDd left ventricular end-diastolic diameter, LVEF left ventricular ejection fraction, LVSd left ventricular end-systolic diameter, LVEDV left ventricular end-diastolic volume, LVESV left ventricular end-systolic volume, LVMI left ventricular mass index, MR mitral regurgitation, PAEDP pulmonary artery end-diastolic pressure, PAP pulmonary artery pressure, PH pulmonary hypertension, PVR pulmonary vascular resistance, RVol regurgitant volume, RVSP right ventricular systolic pressure, S t ’ tissue Doppler peak systolic velocity of lateral tricuspid annulus, TAPSE tricuspid annular plane systolic excursion
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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