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Table 3 Relationship between DHA/AA (≥0.903) and ACS, subgroup analysis

From: Association between the docosahexaenoic acid to arachidonic acid ratio and acute coronary syndrome: a multicenter observational study

Subgroup DHA/AA ACS N Prevalence Crude OR (95 % CI) Adjusted OR(95 % CI) P-value for interaction
Male ≥0.903 47 688 6.8 % 0.572 (0.391, 0.838) 0.389 (0.211, 0.716) 0.01a
  <0.903 75 660 11.4 %   
Female ≥0.903 18 179 10.1 % 1.982 (0.910, 4.317) 3.820 (0.718, 20.325)
  <0.903 11 206 5.3 %   
Age ≥65 ≥0.903 43 539 8.0 % 0.842 (0.528, 1.343) 0.658 (0.329, 1.317) 0.23
  <0.903 35 375 9.3 %   
Age <65 ≥0.903 22 328 6.7 % 0.620 (0.368, 1.044) 0.312 (0.115, 0.846)
  <0.903 51 491 10.4 %   
Diabetes mellitus, yes ≥0.903 25 345 7.2 % 0.576 (0.341, 0.973) 0.424 (0.197, 0.915) 0.31
  <0.903 40 335 11.9 %   
Diabetes mellitus, no ≥0.903 40 522 7.7 % 0.875 (0.562, 1.361) 0.758 (0.338, 1.700)
  <0.903 46 531 8.7 %   
Hypertension, yes ≥0.903 51 656 7.8 % 0.819 (0.552, 1.216) 0.706 (0.377, 1.320) 0.06a
  <0.903 57 611 9.3 %   
Hypertension, no ≥0.903 14 211 6.6 % 0.554 (0.285, 1.078) 0.162 (0.039, 0.670)
  <0.903 29 255 11.4 %   
Dyslipidemia, yes ≥0.903 46 612 7.5 % 0.656 (0.443, 0.973) 0.447 (0.237, 0.845) 0.15
  <0.903 67 608 11.0 %   
Dyslipidemia, no ≥0.903 19 255 7.5 % 1.013 (0.523, 1.961) 1.139 (0.368, 3.527)
  <0.903 19 258 7.4 %   
Smoking history, yes ≥0.903 40 413 6.8 % 0.652 (0.420, 1.010) 0.475 (0.218, 1.031) 0.68
  <0.903 52 368 14.1 %   
Smoking history, no ≥0.903 25 454 5.5 % 0.795 (0.467, 1.355) 0.598 (0.265, 1.350)
  <0.903 34 498 6.8 %   
Family history of IHD, yes ≥0.903 9 166 5.4 % 0.298 (0.134, 0.661) 0.621 (0.174, 2.219) 0.76
  <0.903 25 155 16.1 %   
Family history of IHD, no ≥0.903 56 701 8.0 % 0.925 (0.633, 1.351) 0.499 (0.266, 0.939)
  <0.903 61 711 8.6 %   
Chronic kidney disease, yes ≥0.903 18 236 7.6 % 0.607 (0.317, 1.161) 0.738 (0.277, 1.963) 0.40
  <0.903 23 192 12.0 %   
Chronic kidney disease, no ≥0.903 21 439 4.8 % 0.582 (0.337, 1.002) 0.439 (0.219, 0.880)
  <0.903 40 503 8.0 %   
Obesity (BMI ≥25), yes ≥0.903 23 319 7.2 % 0.707 (0.402, 1.242) 0.909 (0.376, 2.196) 0.19
  <0.903 31 313 9.9 %   
Obesity (BMI <25), no ≥0.903 42 516 8.1 % 0.777 (0.508, 1.189) 0.425 (0.206, 0.877)
  <0.903 53 518 10.2 %   
History of coronary revascularization, yes ≥0.903 32 232 13.8 % 0.742 (0.452, 1.217) 0.488 (0.243, 0.979) 0.84
  <0.903 44 248 17.7 %   
History of coronary revascularization, no ≥0.903 33 635 5.2 % 0.752 (0.470, 1.203) 0.554 (0.211, 1.454)
  <0.903 42 618 6.8 %   
  1. aindicates statistical signficance for interaction (P < 0.10), OR = odds ratio, CI = confidence interval, ACS = acute coronary syndrome, DHA/AA = docosahexaenoic acid to arachidonic acid ratio, IHD = ischemic heart disease, BMI = body mass index