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Table 1 The main clinical and laboratory parameters of the patient and control groups

From: High circulating osteoprotegerin levels are associated with non-zero blood groups

Parameters Patients (n = 105) Controls (n = 109)
Age *** 64.2 ± 0.98 57.0 ± 1.34
Gender (male) 84 (80) 75 (69)
Diabetes 32 (30.5) 23 (21.1)
Hypertension *** 92 (87.6) 44 (40.4)
Stroke history 12 (11.4) 6 (5.5)
Myocardial infarction history 11 (10.4) 18 (16.5)
CAD*** 72 (68.6) 40 (36.7)
Intermittent claudication 105 (100) no
Critical limb ischemia 30 (28.6) no
Significant carotid stenosis a 10 (13.5) nd
Multiple atherosclerotic involvement*** 21 (20) 4 (3.7)
Haemorheological treatment 105 (100) no
Antihypertensives *** 87 (82.8) 29 (26.6)
Anticoagulants ** 25 (23.8) 10 (9.2)
Statins *** 73 (69.5) 10 (9.2)
Fibrates 10 (9.5) 4 (3.7)
Rate of AB0 blood groups (0/non-0) 0.38 0.49
ABI (lower) 0.48 (0.36–0.60) nd
ABI (mean) 0.59 (0.43–0.73) nd
CIMT (lower) a 1.00 (0.70–1.30) nd
CIMT (mean) a 1.25 (0.7–1.45) nd
OPG [ng/mL] *** 4.64 (3.49–6.54) 3.68 (2.92–4.81)
VWF:Ag [%] 129 (96–174) 116 (94–150)
VWF:CB [%] * 123 (94–163) 107 (88–136)
Fibrinogen [g/L] *** 4.10 (3.04–5.03) 3.00 (2.32–3.50)
Total cholesterol [mmol/L] 4.83 (3.98–5.87) 5.10 (4.29–5.88)
HDL–cholesterol [mmol/L] *** 1.19 (1.03–1.40) 1.52 (1.28–1.74)
Triglycerides [mmol/L] 1.33 (0.96–1.76) 1.20 (0.86–1.74)
CRP [mg/L] 5.03 (2.22–9.67) 4.44 (1.84–6.55)
  1. Age is expressed as mean ± SE, gender as the number of males and their percentage, disease states as number and percentage in brackets, compared to all individuals of the group, parameters are given as median with quartile range in brackets. * p < 0.05, ** p < 0.01, *** p < 0.001 significances of patients to control (Mann–Whitney U test for continuous variables and Fisher’s exact test for categorical variables), aexamined in 74 cases, no = no sign or history at controls, nd = not determined