The type of the functional cardiovascular response to upright posture is associated with arterial stiffness: a cross-sectional study in 470 volunteers

Table 2 Analysis of determinants of arterial stiffness

	Model 1: Constant 1.83258		Model 2: Constant 1.74717
Variable	Coefficient	p-value	Coefficient	p-value
Phenotype: intermediate	0.09103	0.046	0.12729	0.005
Phenotype: sustainer	0.09103	0.022	0.11514	0.005
BMI: middle tertile	0.07742	<0.001	0.07209	0.002
BMI: high tertile	0.12824	<0.001	0.11146	<0.001
Age: middle tertile	0.09143	<0.001	0.08398	<0.001
Age: high tertile	0.23804	<0.001	0.23729	<0.001
Blood pressure ≥135/85 mmHg	0.10273	<0.001	0.08734	<0.001
Female sex	0.03609	0.377	0.08017	0.065
Interaction: female sex and intermediate phenotype	−0.11124	0.043	−0.14789	0.007
Interaction: female sex and sustainer phenotype	−0.07442	0.143	−0.09407	0.071
Fasting plasma triglycerides	-	-	0.05707	0.004

Analysis of explanatory factors for supine pulse wave velocity (after logarithmic transformation) in multivariate analysis. The male sex, constrictor phenotype, lowest BMI tertile, lowest age tertile, and BP < 135/85 mmHg served as reference categories in both models, i.e. for these variables the numeric value of the coefficient is 0
Model 1 was based on phenotype, BMI-category, age-category, BP-category, and sex. Model 1 formula for log(PWV) ~ Constant + phenotype + BMI-category + AGE-category + BP-category + sex + phenotype*sex
Example of interpretation: median log(PWV) for a woman with the sustainer phenotype with BMI and age in the highest tertile and BP ≥ 135/85 mmHg: 1.83258 + 0.09103 + 0.12824 + 0.23804 + 0.10273+ 0.03609 + (-0.07442) = 2.35429; median PWV = exp(2.35429) = 10.53 m/s
Model 2 was based on Model 1 and fasting plasma total, LDL, and HDL cholesterol, triglycerides, glucose, and haematocrit
Model 2 formula for log(PWV) ~ Constant + phenotype + BMI-category + AGE-category + BP-category + sex + phenotype *sex + 0.05707*plasma triglyceride concentration

ISSN: 1471-2261