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Table 1 Demographics and laboratory values in the three phenotypes

From: The type of the functional cardiovascular response to upright posture is associated with arterial stiffness: a cross-sectional study in 470 volunteers

Variable Constrictor Intermediate Sustainer p-value
Number of subjects 109 139 222  
Age (years) 46 (37–53) 46 (38–57) 47 (38–55) 0.216
Female (%) 80 58* 32*† <0.001
BP ≥ 135/85 mmHg (%) in the laboratory 34 42* 51*† 0.009
Body mass index (kg/m2) 23.1 (21.6–25.6) 26.5 (24.1–29.3)* 27.4 (24.8–30.6)* <0.001
Waist circumference (cm)     
 Female 79 (73–87) 86 (79–97)* 88 (82–99)* <0.001
 Male 85 (80–92) 98 (91–99)* 100 (94–107)* <0.001
Smoking (no/present/previous) 66/16/27 90/14/35 121/23/78 0.090
Office systolic BP (mmHg) 134 (119–148) 139 (123–152) 141 (123–157)* 0.007
Office diastolic BP (mmHg) 84 (75–91) 90 (81–98)* 91 (82–99)* <0.001
Haematocrit 0.40 (0.39–0.42) 0.42 (0.39–0.44)* 0.43 (0.41–0.45)*† <0.001
Creatinine (μmol/l) 66 (59–74) 70 (64–80)* 76 (69–84)*† <0.001
eGFR (ml/min/1.73 m2) 89 (80–97) 88 (79–97) 89 (78–99) 0.631
Total Cholesterol (mmol/l) 4.80 (4.20–5.50) 5.20 (4.60–5.80)* 5.20 (4.4–5.8)* 0.018
LDL Cholesterol (mmol/l) 2.45 (2.10–3.18) 3.00 (2.40–3.60)* 3.10 (2.30–3.70)* <0.001
HDL cholesterol (mmol/l 1.78 (1.49–2.13) 1.54 (1.23–1.84)* 1.43 (1.17–1.71)* <0.001
Triglycerides (mmol/l) 0.92 (0.61–1.16) 1.08 (0.82–1.43)* 1.11 (0.76–1.67)*† <0.001
Fasting plasma glucose (mmol/l) 5.2 (4.9–5.4) 5.4 (5.1–5.7)* 5.5 (5.1–5.8)* <0.001
  1. Values are median (25th-75th percentile); BP, blood pressure; eGFR, estimated creatinine-based glomerulus filtration rate using the MDRD formula;23 *p < 0.05 when compared with constrictor phenotype; †p < 0.05 when compared with intermediate phenotype