Table 2 Myoblast and myotubes characteristics in HFrEF patients versus controls

Myogenicity (% Desmin positive cells)

 Myoblasts

92.14 ± 1.76

91.09 ± 1.89

0.608

 Myotubes

90.80 ± 0.43

92.30 ± 1.19

0.485

Growth characteristics

 Maximum cell index (time in hours)

114.5 ± 12.05

136.5 ± 5.16

0.214

 Cell Index (at 90 h)

1.80 ± 0.35

1.0 ± 0.10

0.032

Differentiation capacity

 Differentiation Index (DI)

55.49 ± 2.67

46.57 ± 3.29

0.065

 Deformed Myotubes Index (DMI)

1.96 ± 0.36

3.10 ± 0.74

0.394

 Myogenic Fusion Index (MFI)

57.33 ± 2.40

50.41 ± 1.98

0.093

   < 3 Nuclei

20.67 ± 2.45

26.17 ± 2.55

0.266

  3–10 Nuclei

56.50 ± 4.59

50.17 ± 5.89

0.574

   > 10 Nuclei

21.17 ± 4.64

18.83 ± 2.63

0.905

Viability (% alive cells)

 7-AAD^-

97.83 ± 0.51

97.05 ± 0.60

0.476

 Annexin-V^-

92.25 ± 1.34

90.59 ± 1.66

0.352