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Table 6 Observed and expected gender-specific odds ratios of in-hospital mortality following acute myocardial infarction: sensitivity analysis accounting for sex-specific uncertainty in the prevalence of comorbidity

From: Sex differences in in-hospital mortality following a first acute myocardial infarction: symptomatology, delayed presentation, and hospital setting

Level of uncertaintya

Comorbidity prevalence %, females : males

Odds ratio of females dying compared to males

Expected percent bias

  

Observed unadjusted OR

–

–

–

2.1 (1.5–2.8)

 
  

Expected comorbidity adjusted OR: sensitivity analysisb

 

5 %

40 : 35

2.06

1 %

10 %

45 : 35

2.05

2 %

25 %

60 : 35

2.00

4 %

45 %

80 : 35

1.94

7 %

65 %

100 : 35

1.88

10 %

  1. aUncertainty in the prevalence of comorbidity in females. The assumed prevalence of both females and males was set at 35 % (McManus et al. [31]). The prevalence of comorbidity in females was increased in accordance to the level of uncertainty
  2. bThe sensitivity analysis evaluated the odds ratio while accounting for unmeasured confounding by comorbidity