Skip to main content

Table 1 Cohort characteristics according to classification by body mass index (BMI) definition of normal-weight/overweight

From: Overweight modifies the longitudinal association between uric acid and some components of the metabolic syndrome: The Tromsø Study

  

BMI < 25 kg/m2, n = 2556

BMI ≥ 25 kg/m2, n = 3527

  

SD/%

Pearson correlation with UA

P for Pearson correlation

 

SD/%

Pearson correlation with UA

P for Pearson correlation

P between groups of BMI cut-off

Age, years

 

58.8

±11.3

0.09

<0.001

60.9

±9.1

−0.08

<0.001

<0.001

Sex

Men

1149

45.0 %

0.51

<0.001

1847

52.4 %

0.44

<0.001

<0.001

Women

1407

55.0 %

1680

47.6 %

Systolic blood pressure, mm Hg

 

139.5

±21.7

0.11

<0.001

148.3

±22.1

0.03

0.046

<0.001

Waist circumference, cm

Men

87.7

±5.6

0.45

<0.001

99.5

±7.6

0.39

<0.001

<0.001

Women

77.5

±6.3

91.0

±9.5

Serum HDL, mmol/L

 

1.65

±0.45

−0.28

<0.001

1.46

±0.40

−0.35

<0.001

<0.001

Uric acid μmol/L

Men

334.1

±72.9

377.7

±88.4

<0.001

Women

254.5

±63.4

298.9

±72.0

<0.001

Triglycerides, mmol/L

 

1.27

±0.67

0.45

<0.001

1.73

±0.98

0.55

<0.001

<0.001

Plasma glucose, mmol/L

 

4.64

±0.58

0.03

0.094

4.82

±0.62

0.11

<0.001

<0.001

HBA1C, %

 

5.36

±0.35

0.03

0.229

5.42

±0.37

0.05

0.003

<0.001

Total cholesterol, mmol/L

 

6.56

±1.33

0.07

<0.001

6.89

±1.25

0.01

0.666

<0.001

eGFR, mL/min/1.73 m2

 

94.6

±13.6

−0.23

<0.001

91.6

±13.0

−0.14

<0.001

<0.001

Use of diuretics, n

 

23

0.9 %

0.12

<0.001

78

2.2 %

0.13

<0.001

<0.001

Use of allopurinol, n

 

0

15

0.4 %

0.03

0.113

0.001

Daily smoker, n

 

1026

40.1 %

−0.01

0.503

935

26.5 %

0.03

0.131

<0.001

Alcohol consumption, teetotalers, n

 

1277

50.0 %

0.14

<0.001

1936

54.90 %

0.19

<0.001

0.001

Alcohol consumption, 1–7 units/week, n

 

1186

46.4 %

1435

40.70 %

Alcohol consumption, > 7 units/week, n

 

93

3.6 %

156

4.40 %

Physical activity, n

 

608

23.8 %

0.04

0.044

720

20.4 %

0.03

0.086

0.002

Elevated blood pressure, n

 

1696

66.4 %

0.14

<0.001

2943

83.4 %

0.11

<0.001

<0.001

Central obesity, n

 

95

3.7 %

−0.04

0.058

1631

46.2 %

0.06

<0.001

<0.001

Elevated triglycerides, n

 

252

9.9 %

0.33

<0.001

894

25.3 %

0.41

<0.001

<0.001

Low HDL, n

 

282

11.0 %

0.05

0.007

724

20.5 %

0.18

<0.001

<0.001

Elevated fasting glucose, n

 

15

0.6 %

0.01

0.666

65

1.8 %

0.03

0.104

<0.001

Metabolic syndrome, n

 

91

3.6 %

0.20

<0.001

788

22.3 %

0.32

<0.001

<0.001

  1. The first column in each strata provides means for the continuous variables and numbers for the categories
  2. Elevated blood pressure = blood pressure ≥130/85 mm Hg or treated for hypertension, elevated triglycerides = triglycerides ≥2.28 mmol/L if time since last meal <4 h and ≥1.7 mmol/L if time since last meal ≥4 h or use of lipid lowering drugs, low HDL = HDL < 1.03 mmol/L in men or <1.30 mmol/L in women, elevated fasting glucose = glucose ≥ 7.8 mmol/L if time since last meal <4 h and ≥5.6 mmol/L if time since last meal ≥4 h or treated for elevated glucose, central obesity = waist circumference ≥ 102 cm in men or ≥88 cm in women, MetS = three or more MetS components
  3. Abbreviations: BMI body mass index, UA uric acid, SD standard deviation, HDL high-density lipoprotein, HBA1c hemoglobin A1c, eGFR estimated glomerular filtration rate