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Table 1 Cohort characteristics according to classification by body mass index (BMI) definition of normal-weight/overweight

From: Overweight modifies the longitudinal association between uric acid and some components of the metabolic syndrome: The Tromsø Study

   BMI < 25 kg/m2, n = 2556 BMI ≥ 25 kg/m2, n = 3527
   SD/% Pearson correlation with UA P for Pearson correlation   SD/% Pearson correlation with UA P for Pearson correlation P between groups of BMI cut-off
Age, years   58.8 ±11.3 0.09 <0.001 60.9 ±9.1 −0.08 <0.001 <0.001
Sex Men 1149 45.0 % 0.51 <0.001 1847 52.4 % 0.44 <0.001 <0.001
Women 1407 55.0 % 1680 47.6 %
Systolic blood pressure, mm Hg   139.5 ±21.7 0.11 <0.001 148.3 ±22.1 0.03 0.046 <0.001
Waist circumference, cm Men 87.7 ±5.6 0.45 <0.001 99.5 ±7.6 0.39 <0.001 <0.001
Women 77.5 ±6.3 91.0 ±9.5
Serum HDL, mmol/L   1.65 ±0.45 −0.28 <0.001 1.46 ±0.40 −0.35 <0.001 <0.001
Uric acid μmol/L Men 334.1 ±72.9 377.7 ±88.4 <0.001
Women 254.5 ±63.4 298.9 ±72.0 <0.001
Triglycerides, mmol/L   1.27 ±0.67 0.45 <0.001 1.73 ±0.98 0.55 <0.001 <0.001
Plasma glucose, mmol/L   4.64 ±0.58 0.03 0.094 4.82 ±0.62 0.11 <0.001 <0.001
HBA1C, %   5.36 ±0.35 0.03 0.229 5.42 ±0.37 0.05 0.003 <0.001
Total cholesterol, mmol/L   6.56 ±1.33 0.07 <0.001 6.89 ±1.25 0.01 0.666 <0.001
eGFR, mL/min/1.73 m2   94.6 ±13.6 −0.23 <0.001 91.6 ±13.0 −0.14 <0.001 <0.001
Use of diuretics, n   23 0.9 % 0.12 <0.001 78 2.2 % 0.13 <0.001 <0.001
Use of allopurinol, n   0 15 0.4 % 0.03 0.113 0.001
Daily smoker, n   1026 40.1 % −0.01 0.503 935 26.5 % 0.03 0.131 <0.001
Alcohol consumption, teetotalers, n   1277 50.0 % 0.14 <0.001 1936 54.90 % 0.19 <0.001 0.001
Alcohol consumption, 1–7 units/week, n   1186 46.4 % 1435 40.70 %
Alcohol consumption, > 7 units/week, n   93 3.6 % 156 4.40 %
Physical activity, n   608 23.8 % 0.04 0.044 720 20.4 % 0.03 0.086 0.002
Elevated blood pressure, n   1696 66.4 % 0.14 <0.001 2943 83.4 % 0.11 <0.001 <0.001
Central obesity, n   95 3.7 % −0.04 0.058 1631 46.2 % 0.06 <0.001 <0.001
Elevated triglycerides, n   252 9.9 % 0.33 <0.001 894 25.3 % 0.41 <0.001 <0.001
Low HDL, n   282 11.0 % 0.05 0.007 724 20.5 % 0.18 <0.001 <0.001
Elevated fasting glucose, n   15 0.6 % 0.01 0.666 65 1.8 % 0.03 0.104 <0.001
Metabolic syndrome, n   91 3.6 % 0.20 <0.001 788 22.3 % 0.32 <0.001 <0.001
  1. The first column in each strata provides means for the continuous variables and numbers for the categories
  2. Elevated blood pressure = blood pressure ≥130/85 mm Hg or treated for hypertension, elevated triglycerides = triglycerides ≥2.28 mmol/L if time since last meal <4 h and ≥1.7 mmol/L if time since last meal ≥4 h or use of lipid lowering drugs, low HDL = HDL < 1.03 mmol/L in men or <1.30 mmol/L in women, elevated fasting glucose = glucose ≥ 7.8 mmol/L if time since last meal <4 h and ≥5.6 mmol/L if time since last meal ≥4 h or treated for elevated glucose, central obesity = waist circumference ≥ 102 cm in men or ≥88 cm in women, MetS = three or more MetS components
  3. Abbreviations: BMI body mass index, UA uric acid, SD standard deviation, HDL high-density lipoprotein, HBA1c hemoglobin A1c, eGFR estimated glomerular filtration rate