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Table 2 The association between GDF-15 concentration and ACS prognosis

From: Growth differentiation factor–15 predicts the prognoses of patients with acute coronary syndrome: a meta-analysis

 

Comparison

Participants

RR [95 %CI]

p value

I2

Mortality

     

ACS type

Overall

8903

6.08 [4.79, 7.71]

<0.00001

0 %

 

ACS

4123

6.03 [3.66, 9.93]

<0.00001

11 %

 

NSTEMI

4038

5.94 [4.38, 8.05]

<0.00001

8 %

 

STEMI

742

8.24 [3.35, 20.25]

<0.00001

0 %

Cutoff Point

<1200 VS 1200–1800

5551

2.23 [1.66, 2.99]

<0.00001

0 %

 

1200–1800 VS >1800

4985

2.76 [2.28, 3.34]

<0.00001

0 %

 

<1200 VS >1800

5164

6.22 [4.77, 8.10]

<0.00001

0 %

Follow up duration

>1 years

6744

5.47 [4.18, 7.16]

<0.00001

0 %

≤1 years

2159

8.83 [5.32, 14.66]

<0.00001

0 %

Recurrence of MI

     

ACS type

Overall

7193

1.76 [1.49, 2.07]

<0.00001

5 %

ACS

3501

2.02 [1.56, 2.61]

<0.00001

NA

NSTEMI

3454

1.66 [1.35, 2.03]

<0.00001

0 %

STEMI

238

1.00 [0.39, 2.58]

1.00

NA

Cutoff Point

<1200 VS 1200–1800

3766

1.10 [0.75, 1.59]

0.64

65 %

1200–1800 VS >1800

3402

1.49 [1.17, 1.89]

0.0010

27 %

<1200 VS >1800

3454

1.66 [1.35, 2.03]

<0.00001

0 %

Follow up duration

>1 years

5538

1.84 [1.54, 2.19]

<0.00001

5 %

≤1 years

1655

1.42 [0.96, 2.08]

0.08

0 %

  1. NA not applicable, the units of GDF-15 concentration is ng/L