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Table 3 The HRs for sudden and non-sudden cardiac death and for non-fatal cardiac events

From: Diabetes, glucose tolerance, and the risk of sudden cardiac death

Sudden cardiac death

Normal (n = 6706)

IGT (n = 3806)

P

Diabetes (n = 82)

P

 No. of events

437

336

 

12

 

 Unadjusted HR

1 (reference)

1.51 (1.31–1.74)

<0.001

5.52 (3.10–9.82)

<0.001

 Model 1a

1 (reference)

1.16 (1.00–1.35)

0.045

2.62 (1.46–4.70)

0.001

 Model 2b

1 (reference)

1.14 (0.98–1.32)

0.088

2.40 (1.34–4.33)

0.003

Non-sudden cardiac death

Normal (n = 6706)

IGT (n = 3806)

p

Diabetes (n = 82)

p

 No. of events

697

470

 

23

 

 Unadjusted HR

1 (reference)

1.36 (1.21–1.53)

<0.001

8.43 (5.50–12.81)

<0.001

 Model 1a

1 (reference)

0.94 (0.83–1.06)

0.321

3.05 (1.99–4.67)

<0.001

 Model 2b

1 (reference)

0.92 (0.82–1.04)

0.194

2.90 (1.89–4.46)

<0.001

Non-fatal cardiac events

Normal (n = 6706)

IGT (n = 3806)

p

Diabetes (n = 82)

p

 No. of events

2483

1573

 

56

 

 Unadjusted HR

1 (reference)

1.27 (1.19–1.35)

<0.001

6.47 (4.95–8.44)

<0.001

 Model 1a

1 (reference)

0.99 (0.92–1.05)

0.693

3.63 (2.77–4.75)

<0.001

 Model 2b

1 (reference)

0.99 (0.92–1.05)

0.680

3.50 (2.67–4.59)

<0.001

  1. aModel 1: Adjusted for age, sex, BMI, systolic blood pressure, cholesterol, smoking, and baseline cardiac disease
  2. bModel 2: Adjusted for age, sex, BMI, systolic blood pressure, cholesterol, smoking, baseline cardiac disease, heart rate, QTc, electrocardiographic signs of myocardial infarction, and electrocardiographic signs of coronary artery disease