Can BNP-guided therapy improve health-related quality of life, and do responders to BNP-guided heart failure treatment have improved health-related quality of life? Results from the UPSTEP study

Table 2 The clinically important difference for each SF-36 scale to indicate that the patient moved up (+) or down (-) one response level on only one of the scale items [25] in BNP-guided group, CTR group, responders and non responders

SF-36 scales	Points per state change^a	CTR group	BNP group	Responders	Non responders
PF	5	+	+	0	+
RP	6.25	+	+	+	+
BP	10	+	0	0	0
GH	5	0	0	0	0
VT	6.25	+	+	+	+
SF	12.5	+	0	0	0
RE	8.33	+	0	0	0
MH	5	0	+	+	+

Abbreviations: PF Physical functioning, RP Role limitations due to physical health problems, BP Bodily pain, GH General health, VT Vitality, SF Social functioning, RE Role limitations due to emotional health problems, MH Mental health, BNP B-type natriuretic peptide, CTR conventionally treated group, SF-36 Short Form 36
Note: ^aA state change represents the smallest amount that an SF-36 scale score would change if a patient moved up (+) or down (-) one response level on only one of the scales items according to Wyrwich et al.

ISSN: 1471-2261