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Table 2 mRNA expression for IL-10, TGF-β and FoxP3 before atorvastatin (visit 1) and after 3 months (visit 2)

From: Relationship between regulatory T cells subsets and lipid profile in dyslipidemic patients: a longitudinal study during atorvastatin treatment

 

HS (n = 17)

Pts (n = 30)

  

P* vs Pts

  

P**

  

Visit 1

Visit 2

1

2

Visit 2 vs 1

CD4 + CD25+ cells

      

 IL-10

1.46 (0.202–4.747)

0.455

0.058

1.65 (0.3355–4.100)

1.52 (0.134–3.350)

0.173

 TGFβ

18.070 (11.510–37.770)

0.111

0.178

39.850 (14.850–62.850)

32.300 (15.200–56.000)

0.185

 FoxP3

252.600 (72.520–389.700)

0.811

0.858

138.000 (56.800–581.00)

274.000 (59.900–534.000)

0.417

CD4 + CD25- cells

      

 IL-10

0.018 (0.008–0.321)

0.263

0.171

0.328 (0.105–0.447)

0.101 (0.008–0.230)

0.203

 TGFβ

0.851 (0.317–2.055)

0.097

0.428

1.780 (0.716–4.575)

1.640 (0.297–13.700)

1.000

 FoxP3

0.545 (0.208–0.968)

0.627

0.425

0.574 (0.155–3.090)

0.273 (0.133–0.887)

0.019

  1. Values are expressed as median and 25–75th percentile range
  2. * = Mann Whitney test; ** = Wilcoxon signed rank test