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Table 2 mRNA expression for IL-10, TGF-β and FoxP3 before atorvastatin (visit 1) and after 3 months (visit 2)

From: Relationship between regulatory T cells subsets and lipid profile in dyslipidemic patients: a longitudinal study during atorvastatin treatment

  HS (n = 17) Pts (n = 30)
   P* vs Pts    P**
   Visit 1 Visit 2 1 2 Visit 2 vs 1
CD4 + CD25+ cells       
 IL-10 1.46 (0.202–4.747) 0.455 0.058 1.65 (0.3355–4.100) 1.52 (0.134–3.350) 0.173
 TGFβ 18.070 (11.510–37.770) 0.111 0.178 39.850 (14.850–62.850) 32.300 (15.200–56.000) 0.185
 FoxP3 252.600 (72.520–389.700) 0.811 0.858 138.000 (56.800–581.00) 274.000 (59.900–534.000) 0.417
CD4 + CD25- cells       
 IL-10 0.018 (0.008–0.321) 0.263 0.171 0.328 (0.105–0.447) 0.101 (0.008–0.230) 0.203
 TGFβ 0.851 (0.317–2.055) 0.097 0.428 1.780 (0.716–4.575) 1.640 (0.297–13.700) 1.000
 FoxP3 0.545 (0.208–0.968) 0.627 0.425 0.574 (0.155–3.090) 0.273 (0.133–0.887) 0.019
  1. Values are expressed as median and 25–75th percentile range
  2. * = Mann Whitney test; ** = Wilcoxon signed rank test