Table 2 Characteristics of the studies based in Emergency departments
From: Clinical assessment of patients with chest pain; a systematic review of predictive tools
| Author | Country | Patients for score derivation (n) | Outcome | Patients with outcome n (%) | Maximum time from assessment to out come | Variables | Performance |
|---|---|---|---|---|---|---|---|
| Tierney 1985 [37] | USA | 284 | MI | 35 (12.3) | 3 months |
Diaphoresis PMH of MI ST elevation Q wave |
AUC: 0.85 For patients with 2 factors (risk of MI > 25 %): S:0.79 Sp:0.89 PPV:0.49 NPV:0.97 |
| Grijeels 1995 [38] | Netherlands | 815 |
MI Unstable Angina | 400 (49.1) | At dis-charge |
Gender Radiation of pain Nausea or sweating, PMH of CVD Abnormal ECG | AUC: 0.71 |
| Goodacre 2002 [39] | UK | 893 |
MI Cardiac death Arrhythmia Revascularisation | 81 (9.1) | 1 year |
Radiation of pain Burning pain Nausea/vomiting Exertional pain Tender chest wall |
Radiation of pain: PPV:0.14 (0.11-018) NPV:0.94 (0.91-0.95) Exertional pain: PPV: 0.17 (0.12-0.24) NPV: 0.92 (0.90-0.94) |
| Bassan 2004 [40] | Brazil | 566 |
MI Unstable Angina | 269 (47.5) | Outcome recorded during acute clinical management |
Age Chest pain characteristics PMH of CAD Diabetes ST depression, T wave inversion |
AUC: 0.90 (0.88-0.93) Using cut-off probability of CAD 10 % S: 0.99 Sp:0.41 PPV:0.60 NPV:0.98 |
| Björk 2006 [33] | Sweden | 634 |
MI Unstable Angina | 130 (20.5) | Outcome recorded during acute clinical management |
Age Hypertension Angina pectoris PMH of MI PMH of CABG Short symptoms duration Abnormal ECG |
Derivation cohort AUC: 88.0 For S 0.95 Sp:0.5 PPV:0.33 NPV:0.98 |
| Sánchez 2007 [32] | Spain | 732 | Not having CAD | 533 (72.8) | 1 month |
Age Oppressive pain Pain location PMH of CAD Diabetes |
AUC: 0.91 (0.89-0.93) S:0.17 Sp:1 PPV:1 NPV:0.31 |