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Table 2 Characteristics of the studies based in Emergency departments

From: Clinical assessment of patients with chest pain; a systematic review of predictive tools

Author Country Patients for score derivation (n) Outcome Patients with outcome n (%) Maximum time from assessment to out come Variables Performance
Tierney 1985 [37] USA 284 MI 35 (12.3) 3 months Diaphoresis PMH of MI
ST elevation
Q wave
AUC: 0.85
For patients with 2 factors (risk of MI > 25 %): S:0.79
Sp:0.89
PPV:0.49
NPV:0.97
Grijeels 1995 [38] Netherlands 815 MI
Unstable Angina
400 (49.1) At dis-charge Gender
Radiation of pain
Nausea or sweating, PMH of CVD Abnormal ECG
AUC: 0.71
Goodacre 2002 [39] UK 893 MI
Cardiac death
Arrhythmia
Revascularisation
81 (9.1) 1 year Radiation of pain
Burning pain
Nausea/vomiting
Exertional pain
Tender chest wall
Radiation of pain: PPV:0.14 (0.11-018) NPV:0.94 (0.91-0.95) Exertional pain: PPV: 0.17 (0.12-0.24)
NPV: 0.92 (0.90-0.94)
Bassan 2004 [40] Brazil 566 MI
Unstable Angina
269 (47.5) Outcome recorded during acute clinical management Age
Chest pain characteristics
PMH of CAD
Diabetes
ST depression, T wave inversion
AUC: 0.90
(0.88-0.93)
Using cut-off probability of CAD 10 %
S: 0.99
Sp:0.41
PPV:0.60
NPV:0.98
Björk 2006 [33] Sweden 634 MI
Unstable Angina
130 (20.5) Outcome recorded during acute clinical management Age
Hypertension
Angina pectoris
PMH of MI
PMH of CABG
Short symptoms duration
Abnormal ECG
Derivation cohort
AUC: 88.0
For S 0.95
Sp:0.5
PPV:0.33
NPV:0.98
Sánchez 2007 [32] Spain 732 Not having CAD 533 (72.8) 1 month Age
Oppressive pain
Pain location
PMH of CAD
Diabetes
AUC: 0.91
(0.89-0.93)
S:0.17
Sp:1
PPV:1
NPV:0.31
  1. CABG Coronary Artery Bypass Graft