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Table 1 Characteristics of the studies based in Primary Care

From: Clinical assessment of patients with chest pain; a systematic review of predictive tools

Author Country Patients for score derivation (n) Outcome Patients with outcome n (%) Maximum time between assessment and outcome measure Variables Performance
Soxa 1990 [35] USA 1074 MI
Angina
Coronary insufficiency
424 (39.5) 1 year Age
Gender
Exertional pain
Patient stops activities when pain occurs
PMH of MI
Smoking
Pain relived by NTG
For score > 4
S:0.99
Sp:0.18
PPV:0.45
NPV:0.98
Gencer 2010 [36] Switzerland Germany 661 CAD 85 (12.9) 1 year Age
Gender
CV Risk Known
Pain location
Pain duration Exertional pain
Pain on palpation
PMH of CVD
AUC: 0.95 (0.92-0.97)
For scores < 5
(Lowest 5 % for patients with CAD):S:0.98
Sp:0.71
NPV:0.99
Bösner 2010 [30] Germany Switzerland 1199 CAD 180 (15.0) 6 months Age
Gender
Exertional pain
PMH of CVD
Patient assumes pain of cardiac origin
Pain on palpation
AUC: 0.90 (0.87-0.93)
For a cut-off value of 3 (risk of CAD > 35 %): S:0.86
(0.79-0.92)
Sp:0.75
(0.72-0.78)
PPV:0.35
(0.29-0.41)
NPV:0.97
(0.96-0.98)
  1. MI Myocardial Infarction, PMH Past Medical History, NTG Nitroglycerine, AUC Area Under the Curve, S Sensitivity, Sp Specificity, PPV Positive predictive value, NPV Negative predictive value
  2. aThis study included both patients from Cardiology and Primary Care