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Table 1 Bivariate analysis of the association between earlobe crease and selected cardiovascular risk factors (CoLaus study, Lausanne, 2009-2012)

From: Did Dumbo suffer a heart attack? independent association between earlobe crease and cardiovascular disease

Earlobe crease Absence (n = 3829) Presence (n = 806) P-value
Men (%) 1708 (44.6) 455 (56.5) <0.001
Age (years) 56.3 ± 10.3 63.2 ± 9.7 <0.001
BMI (kg/m2) 25.94 ± 4.53 27.38 ± 4.85 <0.001
BMI categories (%)
 Normal 1749 (46.2) 255 (32.2)  
 Overweight 1448 (38.2) 349 (44.1) <0.001
 Obese 592 (15.6) 187 (23.6)  
Abdominal obesity (%) 1382 (36.3) 362 (45.2) <0.001
Smoking status (%)
 Never 1619 (42.3) 300 (37.2)  
 Former 1358 (35.5) 347 (45.1) <0.001
 Current 852 (22.2) 159 (19.7)  
Blood pressure status    
 SBP (mm Hg) 125 ± 17 131 ± 19 <0.001
 DBP (mm Hg) 78 ± 11 79 ± 11 <0.001
 Hypertension (%) 1409 (36.9) 475 (58.9) <0.001
Lipids (mmol/L)
 Total cholesterol 5.70 ± 1.03 5.68 ± 1.10 0.66
 LDL cholesterol 3.45 ± 0.92 3.44 ± 0.98 0.88
 HDL cholesterol 1.65 ± 0.47 1.59 ± 0.47 <0.001
 Triglycerides 1.34 ± 0.90 1.47 ± 0.91 <0.001*
Glycaemic status
 Glucose (mmol/L) 5.83 ± 1.06 6.20 ± 1.59 <0.001
 Insulin (μIU/mL) 8.06 ± 6.82 9.75 ± 7.74 <0.001*
 Diabetes (%) 343 (9.0) 147 (18.3) <0.001
 HOMA-IR 2.21 ± 2.48 2.86 ± 2.65 <0.001
 High HOMA-IR (%) 925 (24.2) 277 (34.4) <0.001
Metabolic syndrome (%) 1070 (28.2) 337 (42.1) <0.001
  1. Results are expressed as number of participants (%) or as mean ± standard deviation. Statistical analysis by Student’s t-test or by chi-square
  2. BMI body mass index; abdominal obesity and metabolic syndrome are defined by the NCEP ATP-III criteria; hypertension is defined as SBP > 140 or DBP > 90 mm Hg and/or anti-hypertensive medication; LDL low-density lipoprotein; HDL high-density lipoprotein; HOMA-IR homeostatic model assessment of insulin resistance; high HOMA-IR is defined as ≥2.6; diabetes is defined as fasting plasma glucose >7.0 mmol/L and/or anti-diabetes medication
  3. *P-value calculated on log-transformed values