Skip to main content

Table 1 Hemodynamic data based on pressure-volume and infarct size 5 weeks after MI

From: Semaphorin 3A attenuates cardiac autonomic disorders and reduces inducible ventricular arrhythmias in rats with experimental myocardial infarction

 

Sham

MI-CON

MI-GFP

MI-SiRNA

MI-Sema

MI-PBS

n

9

9

10

11

11

9

Infarct size (%)

 

42.7 ± 5.1

42.9 ± 4.7

44.3 ± 5.2

43.5 ± 4.2**

41.3 ± 4.9

HR (beats/min)

419.2 ± 19.1

424.5 ± 17.2*

421.4 ± 21.2

427.3 ± 19.2

419.2 ± 19.1**

420.1 ± 19.2

MAP (mmHg)

109.2 ± 3.7

92.4 ± 6.4*

93.2 ± 7.9

89.7 ± 8.1

92.7 ± 7.3**

93.7 ± 7.7

LVDSP (mmHg)

2.92 ± 0.97

6.3 ± 1.2*

5.8 ± 1.4

5.7 ± 1.6

6.1 ± 1.9**

5.9 ± 1.4

LVESP (mmHg)

119.3 ± 9.2

91.2 ± 5.9*

89.2 ± 6.1

90.2 ± 7.1**

88.3 ± 6.8**

91.4 ± 7.1

EDV (μl)

309.4 ± 21.3

483.2 ± 33.7*

467.6 ± 41.4

475.1 ± 48.1**

471.3 ± 47.4**

469.3 ± 45.3

ESV (μl)

106.1 ± 114

293.4 ± 19.4*

289.2 ± 23.1

291.2 ± 24.1**

289.4 ± 27.3**

285.7 ± 24.2**

EF (%)

61.2 ± 1.7

34.7 ± 0.7*

35.3 ± 06

34.9 ± 0.8

34.2 ± 0.9**

33.9 ± 1.0

dP/dtmax (mmHg/s)

5517.4 ± 129

3696.2 ± 90.2*

3712.7 ± 91.8

3637.4 ± 83.7

3707.2 ± 73.1**

3684.3 ± 80.5

dP/dtmin (mmHg/s)

−3989.1 ± 147

−2379.4 ± 77.5*

−2394.7 ± 90.3

−2427.4 ± 84.3

−2312.5 ± 74.9**

−2419.4 ± 94.2

  1. Values are presented as means ± SD. HR, heart rate; MAP mean arterial pressure, LVEDP LV end-diastolic pressure, LVESP LV end-systolic pressure, EDV end-diastolic volume, ESV end-systolic volume, EF ejection fraction, dP/dtmax and dP/dtmin maximal slope of the systolic pressure increment and the diastolic pressure decrement, respectively.* P < 0.05 vs. sham group, ** P > 0.05 among various MI groups