History of CV event cohort | Modified CHD RE cohort | Moderate-risk cohort | Low-risk cohort | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Without CV events | With CV events | Without CV events | With CV events | Without CV events | With CV events | Without CV events | With CV events | |||||
(N = 10,741) | (N = 10,741) | (N = 90,614) | (N = 90,614) | (N = 7,938) | (N = 7,938) | (N = 12,527) | (N = 12,527) | |||||
N/Mean [%]/(SD) | N/Mean [%]/(SD) | P-valuea | N/Mean [%]/(SD) | N/Mean [%]/(SD) | P-valuea | N/Mean [%]/(SD) | N/Mean [%]/(SD) | P-valuea | N/Mean [%]/(SD) | N/Mean [%]/(SD) | P-valuea | |
All-cause Healthcare Utilization 2 Years Post-index Date | ||||||||||||
Number of Continuous Enrollment Patients | 5928[55.2 %] | 5576[51.9 %] | <0.0001 | 58916[65.0 %] | 53212[58.7 %] | <0.0001 | 5096[64.2 %] | 4662[58.7 %] | <0.0001 | 8844[70.6 %] | 7822[62.4 %] | <0.0001 |
Inpatient LOS (days) | 1.50(7.21) | 4.14(16.22) | <0.0001 | 0.71(4.81) | 2.10(9.46) | <0.0001 | 0.60(4.09) | 1.78(9.78) | <0.0001 | 0.24(1.70) | 0.76(4.36) | <0.0001 |
Number of Visits (PPPM) | ||||||||||||
Inpatient stays | 0.02(0.05) | 0.04(0.09) | <0.0001 | 0.01(0.04) | 0.03(0.07) | <0.0001 | 0.01(0.03) | 0.02(0.06) | <0.0001 | 0.00(0.02) | 0.01(0.04) | <0.0001 |
Outpatient Visitsb | 1.72(1.70) | 2.07(2.01) | <0.0001 | 1.26(1.36) | 1.63(1.65) | <0.0001 | 0.97(1.09) | 1.27(1.31) | <0.0001 | 0.73(0.95) | 0.97(1.13) | <0.0001 |
Outpatient ER Visits | 0.03(0.08) | 0.05(0.13) | <0.0001 | 0.02(0.06) | 0.04(0.09) | <0.0001 | 0.02(0.05) | 0.03(0.08) | <0.0001 | 0.01(0.04) | 0.02(0.07) | <0.0001 |
Outpatient Pharmacy Visits | 1.63(1.52) | 1.96(1.70) | <0.0001 | 1.36(1.28) | 1.78(1.49) | <0.0001 | 1.22(1.15) | 1.67(1.34) | <0.0001 | 0.62(0.87) | 1.22(1.14) | <0.0001 |
Outpatient Office Visits | 0.86(0.86) | 0.94(0.94) | <0.0001 | 0.71(0.78) | 0.83(0.82) | <0.0001 | 0.56(0.67) | 0.67(0.74) | <0.0001 | 0.46(0.67) | 0.53(0.64) | <0.0001 |
All-cause Healthcare Utilization 3 Years Post-index Date | ||||||||||||
Number of Continuous Enrollment Patients | 3994[37.2 %] | 3533[32.9 %] | <0.0001 | 44654[49.3 %] | 38489[42.5 %] | <0.0001 | 3903[49.2 %] | 3485[43.9 %] | <0.0001 | 7188[57.4 %] | 5971[47.7 %] | <0.0001 |
Inpatient LOS (days) | 1.38(7.05) | 3.72(14.25) | <0.0001 | 0.69(4.98) | 1.77(8.28) | <0.0001 | 0.72(5.43) | 1.68(8.17) | <0.0001 | 0.29(2.57) | 0.72(5.57) | <0.0001 |
Number of visits (PPPM) | ||||||||||||
Inpatient Stays | 0.02(0.05) | 0.04(0.09) | <0.0001 | 0.01(0.04) | 0.02(0.07) | <0.0001 | 0.01(0.03) | 0.02(0.07) | <0.0001 | 0.00(0.02) | 0.01(0.04) | <0.0001 |
OutpatientVisitsb | 1.64(1.74) | 1.97(2.14) | <0.0001 | 1.24(1.41) | 1.55(1.65) | <0.0001 | 0.96(1.18) | 1.22(1.35) | <0.0001 | 0.77(0.97) | 0.91(1.16) | <0.0001 |
Outpatient ER Visits | 0.03(0.08) | 0.05(0.11) | <0.0001 | 0.02(0.05) | 0.03(0.10) | <0.0001 | 0.01(0.04) | 0.03(0.09) | <0.0001 | 0.01(0.04) | 0.02(0.06) | <0.0001 |
Outpatient Pharmacy Visits | 1.62(1.49) | 1.94(1.70) | <0.0001 | 1.36(1.29) | 1.75(1.49) | <0.0001 | 1.22(1.15) | 1.60(1.31) | <0.0001 | 0.69(0.91) | 1.20(1.15) | <0.0001 |
Outpatient Office Visits | 0.83(0.86) | 0.87(0.89) | 0.043 | 0.70(0.78) | 0.79(0.81) | <0.0001 | 0.55(0.66) | 0.65(0.75) | <0.0001 | 0.48(0.69) | 0.51(0.63) | 0.012 |