All-cause healthcare utilization 1 month (acute phase) post-index date
|
Number of continuous enrollment patients
|
10577[98.5 %]
|
10282[95.7 %]
|
<0.0001
|
89539[98.8 %]
|
88196[97.3 %]
|
<0.0001
|
7845[98.8 %]
|
7727[97.3 %]
|
<0.0001
|
12428[99.2 %]
|
12317[98.3 %]
|
<0.0001
|
Inpatient LOS (days)
|
0.25(1.94)
|
6.43(6.94)
|
<0.0001
|
0.07(0.90)
|
5.22(5.39)
|
<0.0001
|
0.04(0.61)
|
4.97(4.91)
|
<0.0001
|
0.01(0.35)
|
4.42(4.08)
|
<0.0001
|
Number of patients with Inpatient Visits
|
346[3.3 %]
|
10282[100.0 %]
|
<0.0001
|
1102[1.2 %]
|
88196[100.0 %]
|
<0.0001
|
59[0.8 %]
|
7727[100.0 %]
|
<0.0001
|
32[0 .3 %]
|
12317[100.0 %]
|
<0.0001
|
Number of patients with Outpatient ER Visits
|
387[3.7 %]
|
1503[14.6 %]
|
<0.0001
|
1674[1.9 %]
|
15425[17.5 %]
|
<0.0001
|
124[1.6 %]
|
1663[21.5 %]
|
<0.0001
|
128[1.0 %]
|
3194[25.9 %]
|
<0.0001
|
Number of patients with Outpatient Office Visits
|
5431[51.3 %]
|
7141[69.5 %]
|
<0.0001
|
39190[43.8 %]
|
67063[76.0 %]
|
<0.0001
|
2857[36.4 %]
|
5654[73.2 %]
|
<0.0001
|
3110[25.0 %]
|
9311[75.6 %]
|
<0.0001
|
Number of patients with Outpatient Visitsb
|
7297[69.0 %]
|
9296[90.4 %]
|
<0.0001
|
50185[56.0 %]
|
81329[92.2 %]
|
<0.0001
|
3616[46.1 %]
|
7078[91.6 %]
|
<0.0001
|
3895[31.3 %]
|
11266[91.5 %]
|
<0.0001
|
Number of patients with Outpatient Pharmacy Visits
|
6842[64.7 %]
|
7253[70.5 %]
|
<0.0001
|
56480[63.1 %]
|
67216[76.2 %]
|
<0.0001
|
4736[60.4 %]
|
6266[81.1 %]
|
<0.0001
|
3500[28.2 %]
|
9242[75.0 %]
|
<0.0001
|
Number of visits (PPPM)
| | | | | | | | | | | | |
Inpatient stays
|
0.04(0.21)
|
1.18 (0.48)
|
<0.0001
|
0.01(0.13)
|
1.14(0.42)
|
<0.0001
|
0.01(0.11)
|
1.13(0.40)
|
<0.0001
|
0.00(0.06)
|
1.11(0.36)
|
<0.0001
|
Outpatient Visitsb
|
2.06(2.76)
|
4.64(4.68)
|
<0.0001
|
1.35(2.05)
|
4.29(4.11)
|
<0.0001
|
1.00(1.67)
|
4.17(4.08)
|
<0.0001
|
0.64(1.32)
|
4.24(4.13)
|
<0.0001
|
Outpatient ER Visits
|
0.04(0.22)
|
0.17(0.45)
|
<0.0001
|
0.02(0.16)
|
0.20(0.47)
|
<0.0001
|
0.02(0.14)
|
0.25(0.51)
|
<0.0001
|
0.01(0.12)
|
0.29(0.53)
|
<0.0001
|
Outpatient Pharmacy Visits
|
1.76(1.93)
|
2.29(2.16)
|
<0.0001
|
1.43(1.60)
|
2.34(1.96)
|
<0.0001
|
1.21(1.40)
|
2.28(1.76)
|
<0.0001
|
0.47(0.93)
|
1.74(1.50)
|
<0.0001
|
Outpatient Office Visits
|
1.00(1.50)
|
1.42(1.49)
|
<0.0001
|
0.77(1.31)
|
1.50(1.41)
|
<0.0001
|
0.62(1.19)
|
1.38(1.35)
|
<.0001
|
0.41(0.98)
|
1.39(1.34)
|
<0.0001
|
All-cause Healthcare Utilizations 1 year (31–365 days) post-index date
|
Number of continuous enrollment patients
|
8447[78.6 %]
|
7808[72.7 %]
|
<0.0001
|
75203[83.0 %]
|
70525[77.8 %]
|
<0.0001
|
6588[83.0 %]
|
6165[77.7 %]
|
<.0001
|
10806[86.3 %]
|
10089[80.5 %]
|
<0.0001
|
Inpatient LOS (days)
|
2.06(13.01)
|
6.61(20.85)
|
<0.0001
|
0.70(4.94)
|
3.20(13.27)
|
<0.0001
|
0.51(3.98)
|
2.46(11.26)
|
<.0001
|
0.23(2.72)
|
1.75(10.73)
|
<0.0001
|
Number of patients with Inpatient Visits
|
1304[15.4 %]
|
2916[37.3 %]
|
<0.0001
|
6442[8.6 %]
|
18316[26.0 %]
|
<0.0001
|
445[6.8 %]
|
1439[23.3 %]
|
<.0001
|
376[3.5 %]
|
1747[17.3 %]
|
<0.0001
|
Number of patients with Outpatient ER Visits
|
2062[24.4 %]
|
2767[35.4 %]
|
<0.0001
|
11284[15.0 %]
|
19597[27.8 %]
|
<0.0001
|
876[13.3 %]
|
1558[25.3 %]
|
<.0001
|
1109[10.3 %]
|
2370[23.5 %]
|
<0.0001
|
Number of patients with Outpatient Office Visits
|
7810[92.5 %]
|
7423[95.1 %]
|
<0.0001
|
70005[93.1 %]
|
68022[96.5 %]
|
<0.0001
|
5692[86.4 %]
|
5801[94.1 %]
|
<.0001
|
8009[74.1 %]
|
9396[93.1 %]
|
<0.0001
|
Number of patients with Outpatient Visitsb
|
8216[97.3 %]
|
7726[98.9 %]
|
<0.0001
|
72302[96.1 %]
|
69833[99.0 %]
|
<0.0001
|
6028[91.5 %]
|
6048[98.1 %]
|
<.0001
|
8569[79.3 %]
|
9777[96.9 %]
|
<0.0001
|
Number of patients with Outpatient Pharmacy Visits
|
6685[79.1 %]
|
6397[81.9 %]
|
<0.0001
|
61668[82.0 %]
|
59379[84.2 %]
|
<0.0001
|
5440[82.6 %]
|
5411[87.8 %]
|
<.0001
|
6611[61.2 %]
|
8281[82.1 %]
|
<0.0001
|
Number of visits PPPM
| | | | | | | | | | | | |
Inpatient stays
|
0.02(0.06)
|
0.06(0.11)
|
<0.0001
|
0.01(0.04)
|
0.04(0.09)
|
<0.0001
|
0.01(0.03)
|
0.03(0.07)
|
<.0001
|
0.00(0.02)
|
0.02(0.06)
|
<0.0001
|
OutpatientVisitsb
|
1.81(1.71)
|
2.62(2.20)
|
<0.0001
|
1.28(1.33)
|
2.13(1.86)
|
<0.0001
|
0.95(1.09)
|
1.74(1.62)
|
<.0001
|
0.65(0.88)
|
1.50(1.47)
|
<0.0001
|
Outpatient ER Visits
|
0.04(0.08)
|
0.06(0.14)
|
<0.0001
|
0.02(0.06)
|
0.04(0.10)
|
<0.0001
|
0.02(0.05)
|
0.04(0.09)
|
<.0001
|
0.01(0.04)
|
0.03(0.08)
|
<0.0001
|
Outpatient Pharmacy Visits
|
1.66(1.53)
|
2.05(1.69)
|
<0.0001
|
1.37(1.28)
|
1.87(1.48)
|
<0.0001
|
1.18(1.12)
|
1.80(1.32)
|
<.0001
|
0.50(0.75)
|
1.29(1.11)
|
<0.0001
|
Outpatient Office Visits
|
0.90(0.88)
|
1.10(0.99)
|
<0.0001
|
0.73(0.79)
|
0.98(0.87)
|
<0.0001
|
0.57(0.71)
|
0.80(0.80)
|
<0.0001
|
0.42(0.64)
|
0.68(0.73)
|
<0.0001
|
All-cause healthcare utilization 2 years post-index date
|
Number of patients with Inpatient Visits
|
848[14.3 %]
|
1660[29.8 %]
|
<0.0001
|
5208[8.8 %]
|
11020[20.7 %]
|
<0.0001
|
394[7.7 %]
|
856[18.4 %]
|
<0.0001
|
391[4.4 %]
|
915[11.7 %]
|
<0.0001
|
Number of patients with Outpatient ER Visits
|
1455[24.5 %]
|
1845[33.1 %]
|
<0.0001
|
9514[16.1 %]
|
13799[25.9 %]
|
<0.0001
|
759[14.9 %]
|
1134[24.3 %]
|
<0.0001
|
963[10.9 %]
|
1583[20.2 %]
|
<0.0001
|
Number of patients with Outpatient Office Visits
|
5371[90.6 %]
|
5084[91.2 %]
|
0.286
|
54074[91.8 %]
|
49751[93.5 %]
|
<0.0001
|
4433[87.0 %]
|
4213[90.4 %]
|
<0.0001
|
6969[78.8 %]
|
6944[88.8 %]
|
<0.0001
|
Number of patients with Outpatient Visitsb
|
5668[95.6 %]
|
5352[96.0 %]
|
0.325
|
55882[94.9 %]
|
51394[96.6 %]
|
<0.0001
|
4669[91.6 %]
|
4445[95.3 %]
|
<0.0001
|
7377[83.4 %]
|
7286[93.1 %]
|
<0.0001
|
Number of patients with Outpatient Pharmacy Visits
|
4720[79.6 %]
|
4549[81.6 %]
|
0.008
|
48323[82.0 %]
|
44590[83.8 %]
|
<0.0001
|
4228[83.0 %]
|
4015[86.1 %]
|
<0.0001
|
5886[66.6 %]
|
6324[80.8 %]
|
<0.0001
|
All-cause healthcare utilization 3 years post-index date
|
Number of patients with Inpatient Visits
|
563[14.1 %]
|
961[27.2 %]
|
<0.0001
|
3941[8.8 %]
|
7146[18.6 %]
|
<0.0001
|
288[7.4 %]
|
590[16.9 %]
|
<0.0001
|
325[4.5 %]
|
617[10.3 %]
|
<0.0001
|
Number of patients with Outpatient ER Visits
|
965[24.2 %]
|
1173[33.2 %]
|
<0.0001
|
7049[15.8 %]
|
9683[25.2 %]
|
<0.0001
|
503[12.9 %]
|
817[23.4 %]
|
<0.0001
|
804[11.2 %]
|
1187[19.9 %]
|
<0.0001
|
Number of patients with Outpatient Office Visits
|
3569[89.4 %]
|
3150[89.2 %]
|
0.78
|
40638[91.0 %]
|
35419[92.0 %]
|
<0.0001
|
3420[87.6 %]
|
3095[88.8 %]
|
0.115
|
5871[81.7 %]
|
5209[87.2 %]
|
<0.0001
|
Number of patients with Outpatient Visitsb
|
3775[94.5 %]
|
3335[94.4 %]
|
0.819
|
42139[94.4 %]
|
36762[95.5 %]
|
<0.0001
|
3587[91.9 %]
|
3272[93.9 %]
|
0.001
|
6194[86.2 %]
|
5468[91.6 %]
|
<0.0001
|
Number of patients with Outpatient Pharmacy Visits
|
3216[80.5 %]
|
2908[82.3 %]
|
0.047
|
36437[81.6 %]
|
32319[84.0 %]
|
<0.0001
|
3221[82.5 %]
|
2958[84.9 %]
|
0.006
|
4991[69.4 %]
|
4804[80.5 %]
|
<0.0001
|