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Table 1 PSM-adjusted 12-month pre-index demographic and clinical characteristics for hyperlipidemic patients with and without new CV events

From: Clinical and economic burden associated with cardiovascular events among patients with hyperlipidemia: a retrospective cohort study

 

History of CV event cohort

Modified CHD RE Cohort

Moderate risk cohort

Low risk cohort

Without CV events

With CV events

 

Without CV events

With CV events

 

Without CV events

With CV events

 

Without CV events

With CV events

 

(N = 10741)

(N = 10741)

(N = 90614)

(N = 90614)

(N = 7938)

(N = 7938)

(N = 12527)

(N = 12527)

Mean [%]/(SD)

Mean [%]/(SD)

P-valuea

STD

Mean [%]/(SD)

Mean [%]/(SD)

P-Valuea

STD

Mean [%]/(SD)

Mean [%]/(SD)

P-valuea

STD

Mean [%]/(SD)

Mean [%]/(SD)

P-valuea

STD

Age

73.66(13.15)

71.76(12.18)

<0.0001

 

65.32(12.95)

64.69(12.75)

<0.0001

 

65.58(11.93)

65.45(12.11)

0.503

 

56.18(11.24)

55.86(10.92)

0.022

 

18–24

[0.0 %]

[0.0 %]

N/A

0.0

[0.0 %]

[0.0 %]

0.336

0.5

[0.0 %]

[0.0 %]

N/A

0.0

[0.1 %]

[0.1 %]

0.683

0.5

25–34

[0.1 %]

[0.1 %]

0.781

0.4

[0.3 %]

[0.3 %]

0.189

0.6

[0.0 %]

[0.0 %]

N/A

0.0

[1.1 %]

[1.1 %]

0.952

0.1

35–54

[7.0 %]

[6.0 %]

0.006

3.8

[19.0 %]

[19.7 %]

<0.0001

1.9

[14.6 %]

[14.5 %]

0.946

0.1

[45.6 %]

[45.6 %]

0.970

0.1

55–64

[22.1 %]

[20.9 %]

0.043

2.8

[36.7 %]

[36.4 %]

0.1

0.8

[43.9 %]

[43.8 %]

0.949

0.1

[36.9 %]

[36.9 %]

0.990

0.0

≥65

[70.9 %]

[73.0 %]

0.001

4.6

[44.0 %]

[43.6 %]

0.129

0.7

[41.6 %]

[41.7 %]

0.910

0.2

[16.3 %]

[16.3 %]

0.932

0.1

Male

[66.6 %]

[65.2 %]

0.029

3.0

[65.3 %]

[65.2 %]

0.657

0.2

[66.7 %]

[66.7 %]

0.946

0.1

[64.7 %]

[64.7 %]

0.926

0.1

US geographic region

                

Northeast

[39.3 %]

[39.5 %]

0.769

0.4

[35.5 %]

[35.3 %]

0.366

0.4

[32.1 %]

[32.1 %]

0.973

0.1

[35.2 %]

[35.3 %]

0.874

0.2

Midwest

[22.1 %]

[23.3 %]

0.040

2.8

[25.9 %]

[26.0 %]

0.351

0.4

[28.2 %]

[28.3 %]

0.930

0.1

[26.5 %]

[26.5 %]

0.989

0.0

South

[24.4 %]

[22.6 %]

0.002

4.3

[27.6 %]

[27.6 %]

0.992

0.0

[28.3 %]

[28.1 %]

0.874

0.3

[28.9 %]

[28.8 %]

0.933

0.1

West

[14.2 %]

[14.7 %]

0.351

1.3

[11.1 %]

[11.1 %]

0.929

0.0

[11.4 %]

[11.5 %]

0.960

0.1

[9.4 %]

[9.3 %]

0.914

0.1

Baseline comorbid condition

                

CCI Score

2.72(2.15)

2.82(2.14)

<0.001

4.9

1.23(1.54)

1.21(1.47)

<0.001

1.7

0.32(0.77)

0.31(0.75)

0.876

0.3

0.14(0.5)

0.14(0.49)

0.848

0.2

Chronic disease score

5.29(4.06)

5.49(4.19)

<0.001

5.0

4.58(3.62)

4.57(3.65)

0.716

0.2

3.99(2.86)

3.99(2.87)

0.892

0.2

0.97(1.74)

0.97(1.74)

0.957

0.1

Baseline number of inpatient visits PPPM

0.19(0.49)

0.2(0.45)

0.193

1.8

0.04(0.19)

0.04(018)

0.007

1.3

0.01(0.05)

0.01(0.05)

0.817

0.4

0(0.03)

0(0.03)

0.654

0.6

  1. Propensity score matching was applied for each cardiovascular disease risk cohort using covariates: age group, gender, US region, baseline Charlson comorbidity index score, Chronic Disease Score, comorbidities (hypertension, arrhythmias, metabolic syndrome, liver disease, obesity and chronic kidney disease) and number of inpatient admissions per patient per month.
  2. CHD RE coronary heart disease risk equivalent, SD standard deviation, STD standardized difference, CV cardiovascular, CVD cardiovascular disease, PPPM per patient per month, PSM propensity score matching
  3. aChi-square tests were used to evaluate the statistical significance of differences in categorical variables; student t-tests were used for the continuous variables
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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