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Fig. 3 | BMC Cardiovascular Disorders

Fig. 3

From: Regulation of SCN3B/scn3b by Interleukin 2 (IL-2): IL-2 modulates SCN3B/scn3b transcript expression and increases sodium current in myocardial cells

Fig. 3

Interleukin 2 (IL-2) increased the sodium current density dependent on SCN3B. a Representative traces for sodium currents without (left) and with (right) treated by IL2were elicited with the current protocol depicted in the inset. b. I-V relation for peak sodium current Nav1.5. Average Nav1.5 sodium current density is greater by treatment of IL2 in the presence of SCN3B. c Histogram of sodium current densities at −20 mV. Means and SEM: Control (−260.6 and 28.1 pF/pA n = 17), IL2 (−355.9 and 28.3 pF/pA n = 21).*p < 0.05

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