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Table 1 Baseline demographics and clinical characteristics of study participants by treatment group in the biocohort (N = 143)a

From: C-Reactive protein reactions to glucose-insulin-potassium infusion and relations to infarct size in patients with acute coronary syndromes

Cohort characteristics

No. (%)

N = 143

GIK (N = 68)

Placebo (N = 75)

Age, mean (SD), y

64.5 (12.9)

63.9 (12.8)

Men

52 (76.5)

52 (69.3)

Race

  

 White

66 (97)

71 (95)

Hispanic ethnicity

3 (4.4)

7 (9.3)

Chief complaint on presentation

  

 Chest pain

59 (86.8)

67 (89.3)

 Shortness of breath

1 (1.5)

3 (4)

 Other b

8 (11.7)

5 (6.7)

Medical history

  

 Diabetes

12 (17.6)

19 (25.3)

 Heart Failure

4 (5.9)

7 (9.3)

 AMI

21 (30.9)

24 (32.0)

Medication history

  

 Statins

30 (44.1)

29 (38.7)

 Aspirin

39 (57.3)

44 (58.7)

Minutes from symptom onset to study drug, median (IQR)

86 (51.5–160.5)

81 (53–123)

Minutes from symptom onset to study drug

 0–30

1 (1.5)

0 (0)

 31–60

21 (30.9)

22 (29.3)

 61–90

9 (13.2)

19 (25.3)

 91–180

12 (17.7)

15 (20.0)

 181–360

10 (14.7)

8 (10.7)

 361–24 h

6 (8.8)

5 (6.7)

 Within 24 h, unspecified

3 (4.4)

4 (5.3)

>24 h

6 (8.8)

2 (2.7)

ACI-TIPI score, mean (SD), %

83 (15.7)

83.1 (12.1)

Hospital reperfusion treatment

  

 Thrombolytic therapy

1 (1.5)

1 (1.3)

 PCI

59 (86.8)

56 (74.7)

 Coronary artery bypass graft

0 (0)

2 (2.7)

Confirmed diagnosis

  

 Acute myocardial infarction

58 (85.3)

68 (90.7)

 Any angina

10 (14.7)

7 (9.3)

Time from study drug to biomarker measurement, median (IQR), hours

  

 Initial

2.5 (1.3–3.3)

2.6 (1.9–3.2)

 6 h

6 (6–6.3)

6 (6–6.2)

 12 h

12 (12–12.2)

12.1 (12–12.3)

  1. AMI indicates acute myocardial infarction; ACI-TIPI acute cardiac ischemia time-insensitive predictive instrument; GIK glucose-insulin-potassium; IQR interquartile range; PCI percutaneous coronary intervention; SD standard deviation
  2. aNo significant differences were noted between GIK and placebo groups
  3. bAbdominal pain, back pain, dizziness, heartburn, loss of consciousness, shoulder pain and weakness