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Table 2 Quantitative aSNR and aCNR evaluation

From: Part 2 – Coronary angiography with gadofosveset trisodium: a prospective intra-subject comparison for dose optimization for 100 % efficiency imaging

 

aSNR

 

aCNR

 

Level

Single dose

Double dose

P value

Single dose

Double dose

P value

Left Ventricle

11.0 ± 4.5

17.3 ± 7.8

<0.001

6.0 ± 2.7

9.0 ± 5.0

0.002

Right Ventricle

10.7 ± 8.4

16.7 ± 11.7

<0.001

5.7 ± 6.8

8.4 ± 9.2

0.006

Desc. Aorta

9.5 ± 4.0

15.6 ± 8.1

<0.001

4.5 ± 2.9

7.2 ± 5.5

0.01

Prox. Aorta

13.1 ± 6.1

21.9 ± 10.6

<0.001

8.1 ± 4.5

13.6 ± 7.7

<0.001

Overall

11.1 ± 6.0

17.9 ± 9.8

<0.001

6.1 ± 4.6

9.5 ± 7.3

<0.001

LMS

10.5 ± 4.8

18.2 ± 8.1

<0.001

5.4 ± 3.6

9.6 ± 6.4

0.002

LAD

14.5 ± 4.3

23.6 ± 8.7

<0.001

9.0 ± 3.7

14.1 ± 8.3

0.02

LCX

10.7 ± 3.5

16.5 ± 4.3

<0.001

5.5 ± 3.1

7.8 ± 4.5

0.09

RCA

15.5 ± 6.6

25.3 ± 11.0

<0.001

10.4 ± 5.1

16.7 ± 10.0

0.01

Overall

12.8 ± 5.4

21.0 ± 9.1

<0.001

7.6 ± 4.5

12.1 ± 8.3

<0.001

Other

      

Myocardium

4.9 ± 2.3

8.3 ± 3.8

<0.001

   
  1. There is higher aSNR and aCNR with double dose gadofosveset
  2. aSNR Apparent signal-to-noise ratio
  3. aCNR Apparent Contrast-to-noise ratio (relative to the myocardium)
  4. LM Left main coronary artery
  5. LAD Left anterior descending coronary artery
  6. LCX Left circumflex coronary artery
  7. RCA Right coronary artery