2006–2010 to week 26 (Period 1) | 2010 from week 27–2012 (Period 2) | p-value | |
---|---|---|---|
n = 362 | n = 141 | ||
Patient related riskfactors | |||
Age (years) | 67 ± 9 | 67 ± 9 | 0.610 |
Sex M/F | 73/289 | 121/20 | 0.121 |
Body mass index (kg/m2) | 28 ± 4 | 28 ± 4 | 0.998 |
Preoperative insulin-like growth factor 1 (mmol/mol) | 46 ± 12 | 44 ± 11 | 0.014 (*) |
Diabetes (%) | 94/268 (26 %) | 45/96 (32 %) | 0.180 |
Preoperative hemoglobin concentrations (g/L) | 140 ± 14 | 141 ± 14 | 0.880 |
Preoperative serum creatinine concentrations (μg/L) | 86 ± 28 | 87 ± 38 | 0.747 |
Chronic obstructive pulmonary disease (%) | 12/350 (3.3 %) | 1/140 (0.7 %) | 0.098 |
Corticoid steroid treatment (%) | 6/356 (1.7 %) | 8/133 (5.7 %) | 0.014 (*) |
Current smoking/smoked the last 2 months/never smoked | 46/246/70 | 15/104/22 | 0.444 |
Ejection fraction (%) | 48 ± 9 | 49 ± 8 | 0.041 (*) |
Intraoperative risk factors | |||
Number of saphenous vein grafts (n) | 3 ± 1 | 3 ± 1 | 0.982 |
Internal mammary artery 0/1/2 | 30/330/2 | 13/128/0 | 0.646 |
Duration of cardiopulmonary by-pass time (min) | 85 ± 28 | 85 ± 29 | 0.744 |
Duration of aortic cross clamp time (min) | 47 ± 19 | 48 ± 20 | 0.818 |
Postoperative risk factors | |||
Erythrocyte transfusion day 0 (%) | 118/244 (32.6 %) | 36/105 (25.5 %) | 0.123 |
Erythrocyte transfusion day 1 (%) | 61/301 (16.9 %) | 20/121 (14.2 %) | 0.465 |
Erythrocyte transfusion day 2 (%) | 66/296 (18.2 %) | 13/128 (9.2 %) | 0.013 (*) |
Mean blood glucose concentration day 0 (mmol/L) | 7.7 ± 1.3 | 8.2 ± 1.7 | 0.000 (***) |
Mean blood glucose concentration day 1 (mmol/L) | 8.2 ± 1.6 | 8.3 ± 1.8 | 0.408 |
Mean blood glucose concentration day 2 (mmol/L) | 9.0 ± 2.3 | 8.9 ± 2.3 | 0.634 |