Relationship between the A(8002)G intronic polymorphism of pre-pro-endothelin-1 gene and the endothelin-1 concentration among Tunisian coronary patients

Table 3 Genotypes (associated with the ET-1 serum level) distribution among patients and controls

	Allele frequencies	Genotypes	ET-1 (nmol/L)	P
Patients (157)	F(A) = 0.22	AA (12 %)	10.38 ± 4.6	a NS
	F(G) = 0.78	AG (20 %)	12.33 ± 3.1	b 0.001
	F(G) = 0.78	GG (68 %)	16.9 ± 4.2	c 0.001
Controls (142)	F(A) = 0.65	AA (54 %)	5.61 ± 1.3	a 0.001
	F(G) = 0.35	AG (22.5 %)	7.27 ± 1.2	b 0.001
	F(G) = 0.35	GG (23.5 %)	9.3 ± 2.8	c 0.001

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